{"id":"W3158929441","doi":"10.3389/fonc.2021.674492","title":"Altered T Follicular Helper Cell Subsets and Function in Chronic Lymphocytic Leukemia","year":2021,"lang":"en","type":"article","venue":"Frontiers in Oncology","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"CancerCare Manitoba; Manitoba Health; Research Institute in Oncology and Hematology; University of Manitoba","funders":"Canadian Institutes of Health Research; Leukemia and Lymphoma Society of Canada; CancerCare Manitoba Foundation; Research Manitoba; Leukemia and Lymphoma Society","keywords":"Chronic lymphocytic leukemia; T cell; clone (Java method); CD40; Immunology; Bone marrow; Biology; Immunophenotyping; Cancer research; Leukemia; Cytotoxic T cell; Flow cytometry; Immune system; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001653987,0.000156663,0.0001374159,0.0006532737,0.000149061,0.000318213,0.0001156254,0.0002493799,0.0009496925],"category_scores_gemma":[0.0001841589,0.00008677055,0.00008567397,0.0002705823,0.0002294048,0.0002233657,0.0001685626,0.0002121,0.00020536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002515199,"about_ca_system_score_gemma":0.000128086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000575867,"about_ca_topic_score_gemma":0.0005895787,"domain_scores_codex":[0.9999034,0.00001902127,0.000008090235,0.0000171451,0.00001915814,0.00003310874],"domain_scores_gemma":[0.9999012,0.00002105535,0.00003245401,0.000008317546,0.00001095285,0.00002601084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00143128,0.0001088351,0.08494406,0.0001179558,0.00001549017,0.001102586,0.0003238771,0.0001046227,0.8878389,0.0003431861,0.0001930218,0.02347619],"study_design_scores_gemma":[0.0001299278,0.001903314,0.7763353,0.00004070342,0.00007263917,0.01310467,0.0009723222,0.001175131,0.1946328,0.0009245455,0.01068504,0.00002363801],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979807,0.001285869,0.0001673738,0.00001819691,0.000002565884,0.00000476951,0.00005875531,0.00001351418,0.0004682482],"genre_scores_gemma":[0.9988247,0.0005297644,0.000155406,0.00001417526,0.000009755531,0.000006866787,0.00009187081,0.000002593574,0.0003648075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009496925,"threshold_uncertainty_score":0.003176987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01461244491747644,"score_gpt":0.2898263679799731,"score_spread":0.2752139230624967,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}