{"id":"W3158956437","doi":"10.1210/jendso/bvab048.1399","title":"Switch Data From the Open-Label Extension of the Pivotal Phase 3 Study of Once Weekly Somatrogon Compared to Daily Somatropin in Pediatric Patients With Growth Hormone Deficiency (pGHD)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; OPKO Health (Canada)","funders":"","keywords":"Medicine; Cohort; Soma; Pediatrics; Somatropin; Internal medicine; Growth hormone deficiency; Endocrinology; Growth hormone; Hormone; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002925508,0.001030491,0.001674217,0.0002761492,0.0003509774,0.0008778099,0.0007218981,0.0009888714,0.006245987],"category_scores_gemma":[0.002407323,0.0003771017,0.001787437,0.0003471629,0.0007465293,0.0008306559,0.0004231595,0.002160863,0.0006390933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007437143,"about_ca_system_score_gemma":0.001314705,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006728544,"about_ca_topic_score_gemma":0.002131392,"domain_scores_codex":[0.9985381,0.0009332377,0.00008981636,0.0001476949,0.0001218656,0.0001691416],"domain_scores_gemma":[0.9977239,0.0008296839,0.0005486962,0.0002267927,0.0001247708,0.0005462126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9565578,0.006616235,0.005135371,0.0003280179,0.0009251,0.00007972073,0.0001048851,0.0003770399,0.00572312,0.0001261939,0.001589969,0.02243656],"study_design_scores_gemma":[0.6767675,0.2966055,0.02033282,0.00005666139,0.0006588429,0.0001721109,0.00006794187,0.0003880135,0.001948006,0.0001533139,0.002827323,0.00002199037],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909551,0.002108249,0.0003486402,0.0004174983,0.0001480958,0.001344333,0.00276632,0.00004711825,0.001864536],"genre_scores_gemma":[0.9889186,0.001105593,0.001148881,0.0007660868,0.0002143641,0.001761792,0.004492166,0.00003303742,0.001559396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006245987,"threshold_uncertainty_score":0.02089494,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04938254642750667,"score_gpt":0.3261606173334953,"score_spread":0.2767780709059887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}