{"id":"W3158956437","doi":"10.1210/jendso/bvab048.1399","title":"Switch Data From the Open-Label Extension of the Pivotal Phase 3 Study of Once Weekly Somatrogon Compared to Daily Somatropin in Pediatric Patients With Growth Hormone Deficiency (pGHD)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; OPKO Health (Canada)","funders":"","keywords":"Medicine; Cohort; Soma; Pediatrics; Somatropin; Internal medicine; Growth hormone deficiency; Endocrinology; Growth hormone; Hormone; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003831555,0.0001721151,0.0005097118,0.00002625265,0.0001470145,0.00003263752,0.001424832,0.00002920727,0.000005331858],"category_scores_gemma":[0.001155286,0.00007947862,0.0001273616,0.0007452064,0.00007047139,0.000200172,0.001620474,0.000503054,6.907508e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006295484,"about_ca_system_score_gemma":0.0003115639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005871666,"about_ca_topic_score_gemma":0.000109051,"domain_scores_codex":[0.9976406,0.0002153308,0.0007238064,0.0002464347,0.0009369311,0.0002368644],"domain_scores_gemma":[0.997165,0.0004748444,0.0007216246,0.001017401,0.0005242612,0.00009690935],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001391375,0.01106822,0.9572725,0.00005401389,0.0002142869,0.00005048299,0.002484423,0.0002192504,0.004492105,0.00001084087,0.02216337,0.0005791918],"study_design_scores_gemma":[0.0247855,0.001926753,0.9660098,0.0003498642,0.0006428942,0.00004625128,0.004315421,0.0006076145,0.001121202,0.00003977978,0.0000422158,0.0001127121],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957877,0.001112089,0.0001047364,0.001995977,0.0001972332,0.0006117771,0.0001512916,0.000004782528,0.00003436888],"genre_scores_gemma":[0.9974449,0.0001241986,0.001955416,0.0002663244,0.0001467411,0.00000297072,0.00001871531,0.00001754147,0.00002321684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02339413,"threshold_uncertainty_score":0.3241044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04938254642750667,"score_gpt":0.3261606173334953,"score_spread":0.2767780709059887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}