{"id":"W3158986043","doi":"10.1001/jamapsychiatry.2021.0638","title":"Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis","year":2021,"lang":"en","type":"review","venue":"JAMA Psychiatry","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":135,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Douglas College; McGill University","funders":"Janssen Pharmaceuticals; National Center for Advancing Translational Sciences; Det Sundhedsvidenskabelige Fakultet, Københavns Universitet; National Institute of Mental Health; Helse Sør-Øst RHF; National Health and Medical Research Council; Canadian Institutes of Health Research; NIHR Maudsley Biomedical Research Centre; Xiangya Hospital, Central South University; Department of Psychiatry, Columbia University; NIH Clinical Center; University of California, Irvine; University of California, San Francisco; National Institutes of Health; Novo Nordisk Fonden; Universitätsspital Zürich; Medical Research Council; Zhejiang University; University of Tokyo; Seoul National University Hospital; Meiji Seika Pharma; Karolinska Institutet; Department of Health and Aged Care, Australian Government; Instituto de Salud Carlos III; National Natural Science Foundation of China; National Research Foundation of Korea; Lundbeckfonden; Institute of Psychiatry, Psychology and Neuroscience, King’s College London; Ministerio de Economía y Competitividad; Lee Kong Chian School of Medicine, Nanyang Technological University; Universitetet i Oslo; Universität zu Lübeck; Consejo Nacional de Ciencia y Tecnología; TrygFonden; Central South University; University of Toronto; Generalitat de Catalunya; Diakonhjemmet; Russian Foundation for Basic Research; Vrije Universiteit Amsterdam; Swinburne University of Technology; College of Medicine, Seoul National University; Universität Heidelberg; Nanyang Technological University; Japan Society for the Promotion of Science; Astellas Pharma; University of Edinburgh; European Commission; European Regional Development Fund; Universitat de Barcelona; University of Roehampton; King's College London; Universitetet i Stavanger; Universität Zürich; Sunovion; National Alliance for Research on Schizophrenia and Depression; South London and Maudsley NHS Foundation Trust; Faculty of Health and Medical Sciences, University of Western Australia; National University of Singapore; National Institute for Health and Care Research; National Research Foundation; Rush University; Seoul National University; National Medical Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Veterans Affairs; University of Pittsburgh; Universiteit Maastricht; Norges Forskningsråd; Australian Government; H. Lundbeck A/S; Fundación Alicia Koplowitz; Georgia State University; University of Maryland, Baltimore County; Brain and Behavior Research Foundation; McGill University; Japan Agency for Medical Research and Development; Maryland Department of Health and Mental Hygiene; Region Hovedstaden; University of Bern; Medical Center, University of Pittsburgh; New York City Department of Health and Mental Hygiene; Sir Run Run Shaw Hospital; Sistema Nacional de Investigadores; Universität Basel; Wellcome Trust; Eisai; University of Southern California; National Science Foundation; Horizon 2020 Framework Programme; University of Minnesota; Brigham and Women's Hospital","keywords":"Psychosis; Magnetic resonance imaging; Psychiatry; Psychology; Medicine; Association (psychology); Functional magnetic resonance imaging; Neuroscience; Psychotherapist; Radiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001568188,0.0005835275,0.002659533,0.0004565626,0.0001409687,0.00006987913,0.0002968639,0.0005538518,0.00007694201],"category_scores_gemma":[0.0008829794,0.0004301284,0.000802252,0.0009139426,0.00008685352,0.00009016885,0.00008660467,0.00100206,0.00001397513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008272048,"about_ca_system_score_gemma":0.001688142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002033451,"about_ca_topic_score_gemma":0.002774562,"domain_scores_codex":[0.9949027,0.0007673237,0.001655899,0.0009999371,0.001003286,0.0006708894],"domain_scores_gemma":[0.9963531,0.001095689,0.001229978,0.0007502345,0.0003562707,0.0002147639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0005291765,0.0001187185,0.4845244,0.00216824,0.000454252,0.0000060129,0.00001513499,6.273498e-8,7.579372e-9,0.00007890174,0.007999633,0.5041054],"study_design_scores_gemma":[0.01263154,0.0006468616,0.6454974,0.03281737,0.003045787,0.00008952282,0.00003450169,0.000006148472,0.000001058004,0.0008185743,0.3038884,0.0005228409],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01208115,0.9802839,0.00001982918,0.003386549,0.0009494532,0.002264496,0.0009420401,0.00003599989,0.00003659794],"genre_scores_gemma":[0.000494883,0.9309739,0.06615129,0.0002008213,0.0005349453,0.0006757381,0.0006537255,0.0001029871,0.0002116514],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.5035827,"threshold_uncertainty_score":0.999815,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04392097170514179,"score_gpt":0.385376630003511,"score_spread":0.3414556582983692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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