{"id":"W3159041255","doi":"10.1007/s12609-021-00407-1","title":"Ductal carcinoma in situ (DCIS)—precision medicine for de-escalation","year":2021,"lang":"en","type":"article","venue":"Current Breast Cancer Reports","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Surgical oncology; Ductal carcinoma; Biomarker; Oncology; Internal medicine; Breast cancer; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00426347,0.0003864285,0.001110181,0.000925854,0.0002680963,0.00200276,0.0006245566,0.0007146602,0.004102258],"category_scores_gemma":[0.003761995,0.0001813974,0.0006027245,0.001284355,0.0008299774,0.00138621,0.0006155886,0.001648062,0.0006486115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001364562,"about_ca_system_score_gemma":0.001236838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006729875,"about_ca_topic_score_gemma":0.0009137326,"domain_scores_codex":[0.9988391,0.000507334,0.00008058414,0.0001813652,0.0003096651,0.00008196252],"domain_scores_gemma":[0.9973729,0.001504772,0.0004362094,0.0002975845,0.0002819828,0.0001065552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001525013,0.0003559696,0.007308742,0.002528037,0.0004394485,0.0001857549,0.0001089605,0.0007216019,0.02082016,0.0219979,0.0164152,0.9275932],"study_design_scores_gemma":[0.00107377,0.009683346,0.04527837,0.004056078,0.001800436,0.004417391,0.0006472149,0.002286721,0.07602912,0.05770721,0.7968746,0.0001457218],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03662325,0.8866205,0.0105583,0.04046106,0.00233745,0.0001952874,0.0007264918,0.0002045663,0.02227305],"genre_scores_gemma":[0.4416512,0.5051601,0.01527421,0.02213087,0.005287639,0.000248465,0.001155409,0.00007656191,0.009015552],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00426347,"threshold_uncertainty_score":0.02254766,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02048381260008637,"score_gpt":0.3220882779578356,"score_spread":0.3016044653577492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}