{"id":"W3159073875","doi":"10.1038/s41591-021-01355-0","title":"Delayed production of neutralizing antibodies correlates with fatal COVID-19","year":2021,"lang":"en","type":"article","venue":"Nature Medicine","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":263,"is_retracted":false,"has_abstract":false,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"National Institute for Occupational Safety and Health; National Institute on Aging; National Center for Advancing Translational Sciences; Yale School of Public Health, Yale University; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Gruber Foundation; Yale University; National Science Foundation; U.S. Department of Health and Human Services; Pew Charitable Trusts; G. Harold and Leila Y. Mathers Foundation; U.S. Department of Veterans Affairs; Ludwig Family Foundation; National Institute of Allergy and Infectious Diseases; Howard Hughes Medical Institute","keywords":"Coronavirus disease 2019 (COVID-19); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Antibody; 2019-20 coronavirus outbreak; Neutralizing antibody; Betacoronavirus; Coronavirus Infections; Biology; Medicine; Immunology; Outbreak; Disease; Internal medicine; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000435586,0.0002062348,0.000524769,0.0002532177,0.00009797428,0.0000073976,0.0001127694,0.0002825186,0.00005024177],"category_scores_gemma":[0.002370256,0.0001340803,0.00006776151,0.0009209,0.0004243213,0.00008666469,0.00005061211,0.001025806,0.000007676012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001113365,"about_ca_system_score_gemma":0.0007197537,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001754233,"about_ca_topic_score_gemma":0.0001578826,"domain_scores_codex":[0.9980249,0.00006920826,0.0003200516,0.0004553408,0.0008147147,0.0003157349],"domain_scores_gemma":[0.9985353,0.0001945053,0.0001164531,0.000456144,0.0005898244,0.0001077582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002341507,0.0002767877,0.1805812,0.001337477,0.0004274127,0.001657254,0.002411694,0.000006178183,0.7932617,0.001134459,0.01421639,0.002347932],"study_design_scores_gemma":[0.005803472,0.001595314,0.01366381,0.001047763,0.0004770461,0.002435075,0.002856009,0.000111129,0.8295086,0.0002875377,0.1419348,0.0002794566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682343,0.01302961,0.0002370351,0.01461884,0.0006562689,0.0003952462,0.000006203598,0.0001045241,0.002717968],"genre_scores_gemma":[0.9648473,0.00008688811,0.0003771488,0.0336728,0.0006382226,0.00001126631,0.00005351812,0.00002977404,0.0002830991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1669174,"threshold_uncertainty_score":0.5467637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02953531465965856,"score_gpt":0.3658259923639294,"score_spread":0.3362906777042708,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}