{"id":"W3159093392","doi":"10.1016/j.semcdb.2021.04.011","title":"MicroRNA regulation of prefrontal cortex development and psychiatric risk in adolescence","year":2021,"lang":"en","type":"review","venue":"Seminars in Cell and Developmental Biology","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Prefrontal cortex; microRNA; Schizophrenia (object-oriented programming); Depression (economics); Psychology; Neuroscience; Vulnerability (computing); Cognition; Psychiatry; Clinical psychology; Medicine; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006000755,0.0007992507,0.001180093,0.0006257987,0.0001417262,0.0008010593,0.000558592,0.001036895,0.001578363],"category_scores_gemma":[0.0005777664,0.0002642134,0.0003016752,0.0009699367,0.0005074706,0.0005253124,0.0006217844,0.001286019,0.0009124659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006391278,"about_ca_system_score_gemma":0.0008624109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001088758,"about_ca_topic_score_gemma":0.00224002,"domain_scores_codex":[0.9998972,0.00002425717,0.00001287935,0.00002608407,0.00002474555,0.0000147193],"domain_scores_gemma":[0.9998276,0.00009958173,0.00002379881,0.000005354475,0.00002492473,0.00001866861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002452804,0.00005898108,0.0008244075,0.004285805,0.0001505989,0.0003172103,0.00004685791,0.0006162784,0.003469396,0.00416461,0.02505149,0.9607691],"study_design_scores_gemma":[0.0001061379,0.0001908451,0.01261616,0.003683302,0.000449069,0.002073913,0.000151595,0.0005478291,0.002331074,0.007088222,0.9707051,0.00005670561],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002942512,0.9983134,0.0002094218,0.000332767,0.0001915162,0.000002282872,0.00002739082,0.000009322156,0.000619735],"genre_scores_gemma":[0.002927342,0.9954365,0.0002870256,0.0002542469,0.0002845921,0.00001206272,0.00004834483,0.000003190586,0.0007467503],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001578363,"threshold_uncertainty_score":0.005280137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01014302133337337,"score_gpt":0.2577195427725174,"score_spread":0.247576521439144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}