{"id":"W3159120388","doi":"10.1158/1078-0432.ccr-20-4259","title":"Veliparib in Combination with Carboplatin and Etoposide in Patients with Treatment-Naïve Extensive-Stage Small Cell Lung Cancer: A Phase 2 Randomized Study","year":2021,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Lung Cancer Research Studies","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Veliparib; Medicine; Carboplatin; Internal medicine; Hazard ratio; Etoposide; Placebo; Oncology; Lung cancer; Chemotherapy; Clinical endpoint; Surgery; Confidence interval; Clinical trial; Pathology; Cisplatin; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00271523,0.0002961834,0.001495721,0.000383237,0.0001419101,0.00006720112,0.0001319692,0.0001212577,0.0001157459],"category_scores_gemma":[0.001356686,0.0001963226,0.00008416266,0.001170101,0.0006845252,0.0001082039,0.0002113953,0.001139138,0.000002104914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00131868,"about_ca_system_score_gemma":0.002323743,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01401774,"about_ca_topic_score_gemma":0.03874834,"domain_scores_codex":[0.9943473,0.001840368,0.0008118851,0.0009990735,0.001206944,0.0007944386],"domain_scores_gemma":[0.9950894,0.002478661,0.0001436625,0.0005113344,0.001433902,0.0003429985],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1476266,0.006149598,0.8355177,0.0002557284,0.0004059529,0.0007931791,0.002120271,0.00003453331,0.00003191239,0.00000944669,0.000104022,0.006951049],"study_design_scores_gemma":[0.5311423,0.006445422,0.4584621,0.0006289083,0.0002017372,0.000001074963,0.001617204,0.0008332925,0.0003237854,0.00001198309,0.0001347052,0.0001975403],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858175,0.005261701,0.000005929757,0.001640638,0.00007287865,0.006649102,0.00005099953,0.00002160293,0.0004796489],"genre_scores_gemma":[0.9912095,0.004004363,0.0001145352,0.0001174938,0.00008658539,0.002917153,0.00003994296,0.00005111448,0.001459322],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3835157,"threshold_uncertainty_score":0.992548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1115676410320947,"score_gpt":0.509988089102433,"score_spread":0.3984204480703383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}