{"id":"W3159174847","doi":"10.1002/iub.2502","title":"Glucose‐regulated protein (<scp>GRP78</scp>) is an important cell surface receptor for viral invasion, cancers, and neurological disorders","year":2021,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"","keywords":"Endoplasmic reticulum; Glucose-regulated protein; Cell biology; Biology; Unfolded protein response; Receptor; Heat shock protein; Cancer cell; Cancer research; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007364919,0.0004870531,0.000263733,0.000300535,0.0002436881,0.0003411417,0.0002402648,0.0004344232,0.01079486],"category_scores_gemma":[0.0001336927,0.00005087071,0.0002411877,0.000396821,0.0001600686,0.0001525974,0.0002988301,0.0005081287,0.00486832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003306435,"about_ca_system_score_gemma":0.000167527,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00120501,"about_ca_topic_score_gemma":0.0008449921,"domain_scores_codex":[0.9998944,0.00001526017,0.000006065801,0.00002254211,0.00003983172,0.00002196405],"domain_scores_gemma":[0.9999423,0.0000035372,0.00001691111,0.000003636173,0.00001078159,0.00002284318],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009826501,0.0001502629,0.009170303,0.0005327907,0.000154167,0.004019839,0.00007038243,0.0003444067,0.8140551,0.003562562,0.04495157,0.1220059],"study_design_scores_gemma":[0.0001629814,0.0009229351,0.1234771,0.0001524602,0.0001740601,0.01903486,0.0001751167,0.002369915,0.1803999,0.002767212,0.6702901,0.00007337521],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8400283,0.04920607,0.007827243,0.006569302,0.002996953,0.0002080194,0.01496964,0.001798918,0.07639559],"genre_scores_gemma":[0.8786789,0.01526057,0.005765055,0.002520294,0.0005835156,0.0001587094,0.01479895,0.0001640242,0.08207007],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01079486,"threshold_uncertainty_score":0.03611237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01806282708585393,"score_gpt":0.273362202116283,"score_spread":0.255299375030429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}