{"id":"W3159176128","doi":"10.1007/s12325-021-01732-8","title":"Strategies to Prolong Ketamine’s Efficacy in Adults with Treatment-Resistant Depression","year":2021,"lang":"en","type":"review","venue":"Advances in Therapy","topic":"Treatment of Major Depression","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Auto Workers; University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Medicine; Depression (economics); Ketamine; Rheumatology; Treatment-resistant depression; Internal medicine; Psychiatry; Intensive care medicine; Physical therapy; Major depressive disorder; Mood","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003840354,0.0006948131,0.002477626,0.002095816,0.0002314994,0.001189575,0.0007664177,0.00119752,0.002189886],"category_scores_gemma":[0.01291313,0.0003567249,0.002913659,0.00167567,0.0003872854,0.001197394,0.0005120834,0.0007506215,0.0002021871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009498536,"about_ca_system_score_gemma":0.002504921,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001112931,"about_ca_topic_score_gemma":0.003396764,"domain_scores_codex":[0.9975026,0.001021374,0.0009413936,0.0001647031,0.0003123163,0.00005761232],"domain_scores_gemma":[0.9921387,0.005231013,0.002092858,0.00007484941,0.000371956,0.00009061342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001314401,0.00012264,0.001612108,0.6592917,0.006975987,0.0002057111,0.0002227784,0.00017371,0.0009167478,0.0005166266,0.001580118,0.3270675],"study_design_scores_gemma":[0.006338379,0.006607682,0.02323521,0.7780946,0.09977859,0.002832791,0.0009871257,0.0004246925,0.002905934,0.001537508,0.07715193,0.0001054363],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002139832,0.9969216,0.0001027318,0.0002636652,0.00008407563,0.0001006551,0.00004669055,0.000003415881,0.0003372887],"genre_scores_gemma":[0.03866751,0.9592166,0.0009878372,0.0005545637,0.0001689789,0.0002571848,0.00007018419,0.000001994271,0.00007517446],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003840354,"threshold_uncertainty_score":0.02030998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02944075523617817,"score_gpt":0.3805125747814204,"score_spread":0.3510718195452422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}