{"id":"W3159176820","doi":"10.20944/preprints202103.0696.v1","title":"Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures","year":2021,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; National Research Council Canada; McGill University","funders":"","keywords":"HEK 293 cells; Cell biology; Cell culture; Context (archaeology); Cell; Biogenesis; Microvesicles; Biology; Extracellular vesicle; Chemistry; Molecular biology; Biochemistry; Gene; Genetics; microRNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005938966,0.000435718,0.000476954,0.0001258748,0.00004911695,0.00003330671,0.0006499891,0.0005904838,0.0001540331],"category_scores_gemma":[0.0002721122,0.0005081352,0.0002978476,0.0001684431,0.0001319434,0.00001528801,0.001848736,0.0005627483,0.0000286767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005439917,"about_ca_system_score_gemma":0.0002958124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006830505,"about_ca_topic_score_gemma":0.00002725433,"domain_scores_codex":[0.9966745,0.0003659065,0.0008062284,0.001447818,0.000320797,0.0003847214],"domain_scores_gemma":[0.9973784,0.00001051628,0.0005868717,0.001684798,0.0002232919,0.0001161099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008090652,0.0003480467,0.2004146,0.0005641664,0.00006358181,0.0000315343,0.0006194048,0.000386675,0.7973275,0.000007477651,0.000005374715,0.0001507615],"study_design_scores_gemma":[0.00036048,0.00001870123,0.190561,0.00022214,0.00005083441,0.000003293004,0.000130751,0.00008479661,0.8077567,0.00004349791,0.0003860207,0.0003817768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952827,0.002460979,0.0004761624,0.00005246091,0.0003562303,0.0007551887,0.00006236569,0.00003492898,0.0005189477],"genre_scores_gemma":[0.9949956,0.0005458475,0.000367134,0.00003359251,0.000249691,0.0001091602,0.002377767,0.00007809535,0.001243136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0104292,"threshold_uncertainty_score":0.999737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03666411192169224,"score_gpt":0.2960406219125759,"score_spread":0.2593765099908836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}