{"id":"W3159266731","doi":"10.1002/mdc3.13229","title":"An Open‐Label Phase 2a Study to Evaluate the Safety and Tolerability of Perampanel in Cervical Dystonia","year":2021,"lang":"en","type":"article","venue":"Movement Disorders Clinical Practice","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute; Toronto Western Hospital; University of Toronto; University Health Network","funders":"Arts and Humanities Research Council; University of Toronto","keywords":"Tolerability; Perampanel; Medicine; Cervical dystonia; Adverse effect; Anesthesia; Internal medicine; Botulinum toxin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001891323,0.001302454,0.001900381,0.0004073678,0.0004911707,0.0006303414,0.0011223,0.001282823,0.006562353],"category_scores_gemma":[0.00106,0.0005974714,0.000734366,0.0003573774,0.0009010684,0.0009788171,0.0003273117,0.002030405,0.001007526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008534555,"about_ca_system_score_gemma":0.001514161,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008445369,"about_ca_topic_score_gemma":0.002429448,"domain_scores_codex":[0.9993827,0.0002867562,0.00003671898,0.0001216594,0.00006797761,0.0001040975],"domain_scores_gemma":[0.999057,0.000174399,0.0002148633,0.00009724734,0.00009978437,0.0003566566],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6505914,0.1610182,0.004494686,0.001364766,0.001129318,0.0004261276,0.0004299367,0.001123107,0.1148423,0.0002546993,0.003430421,0.06089504],"study_design_scores_gemma":[0.3603362,0.6254991,0.008018693,0.00002873854,0.0002074293,0.0002486568,0.00005423386,0.0006015422,0.003072014,0.00009074081,0.001820861,0.00002178267],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903753,0.001286454,0.0008432443,0.0003056913,0.00008346247,0.004877029,0.001119909,0.00007634685,0.001032534],"genre_scores_gemma":[0.9832196,0.001126465,0.002899827,0.0008345218,0.000162604,0.007310409,0.001669487,0.00003499176,0.002742243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006562353,"threshold_uncertainty_score":0.02195328,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1089674027534295,"score_gpt":0.4839572319742722,"score_spread":0.3749898292208427,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}