{"id":"W3159332421","doi":"10.3390/cancers13092197","title":"Does Cancer Biology Rely on Parrondo’s Principles?","year":2021,"lang":"en","type":"review","venue":"Cancers","topic":"Mathematical Biology Tumor Growth","field":"Mathematics","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"Direction Générale de l’offre de Soins; Institut National Du Cancer; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Centre National de la Recherche Scientifique; European Commission; MAVA Foundation","keywords":"Biology; Epigenetics; Carcinogenesis; Phenotype; Cancer; Genome instability; Cancer cell; Dormancy; Genetics; DNA damage","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000400042,0.0007068334,0.003142557,0.0001463031,0.00009280498,0.00002759671,0.0006596109,0.0007093541,0.002030305],"category_scores_gemma":[0.001269083,0.0003698633,0.0006960245,0.000318366,0.000270611,0.00002574644,0.000201207,0.0008353469,0.0002094765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002440861,"about_ca_system_score_gemma":0.002133229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005367962,"about_ca_topic_score_gemma":0.0001090023,"domain_scores_codex":[0.9968405,0.0004240056,0.0009746136,0.0009234768,0.0001927894,0.0006445986],"domain_scores_gemma":[0.9962091,0.00168584,0.0007372274,0.001090695,0.00008574841,0.0001913737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000008854739,0.00004920053,0.000008750911,0.0331829,0.0008799509,0.00008837433,0.0001045041,0.000001094227,7.699278e-7,0.5305295,0.01823609,0.41691],"study_design_scores_gemma":[0.0001330024,0.00005033377,1.780505e-7,0.01554966,0.0006527987,0.00001368473,0.00001312271,0.000003801205,0.000009447166,0.01741834,0.9656404,0.0005152822],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001401851,0.9859335,0.00004797,0.00009898441,0.001729173,0.0009089653,0.0003308318,0.0001617496,0.01077485],"genre_scores_gemma":[0.000003884426,0.98957,0.001106176,0.0001983157,0.0004848008,0.001157158,0.0000885853,0.0001273572,0.007263683],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9474043,"threshold_uncertainty_score":0.9998753,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1853029837343836,"score_gpt":0.4326994912412729,"score_spread":0.2473965075068893,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}