{"id":"W3159478847","doi":"10.1101/2021.04.30.442182","title":"LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada; AbCellera (Canada)","funders":"Eli Lilly and Company","keywords":"Potency; Epitope; Neutralization; Virus; Antibody; Mutation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.001171978,0.001325325,0.001889124,0.000847322,0.0003045118,0.0007775421,0.001246606,0.001535111,0.00006320245],"category_scores_gemma":[0.0009114547,0.001374579,0.0007750625,0.00153437,0.0003719491,0.0003485089,0.001500473,0.002715247,0.0005151955],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008553225,"about_ca_system_score_gemma":0.004288291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006852574,"about_ca_topic_score_gemma":0.00002108266,"domain_scores_codex":[0.992366,0.0003754658,0.001252708,0.002583998,0.001641252,0.001780588],"domain_scores_gemma":[0.9938025,0.0001690999,0.0005177463,0.0035891,0.001625102,0.0002964116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002838573,0.0007138631,0.01718031,0.001506842,0.0007426622,0.002798722,0.00002938529,0.000001999156,0.9750737,0.0002986606,0.001358971,0.00001104448],"study_design_scores_gemma":[0.002232459,0.0001750726,0.07172593,0.001268278,0.0004478678,7.55361e-7,0.0000113782,0.0002961022,0.8822154,0.000005044772,0.04037031,0.001251418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895774,0.003547431,0.0007747174,0.000866742,0.00216909,0.001705702,0.0001980992,0.0009103187,0.0002504731],"genre_scores_gemma":[0.9633493,0.0001825512,0.00347636,0.03085801,0.001323732,0.0003776372,0.000001421246,0.0004213795,0.000009568897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09285829,"threshold_uncertainty_score":0.9999498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03913894254033456,"score_gpt":0.3002380888202155,"score_spread":0.2610991462798809,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}