{"id":"W3159540282","doi":"10.1093/ehjqcco/qcab031","title":"Health impact of tafamidis in transthyretin amyloid cardiomyopathy patients: an analysis from the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and the open-label long-term extension studies","year":2021,"lang":"en","type":"article","venue":"European Heart Journal - Quality of Care and Clinical Outcomes","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"EVERSANA (Canada)","funders":"Pfizer","keywords":"Medicine; Internal medicine; Confidence interval; Cohort; Transthyretin; Cardiomyopathy; Oncology; Cardiology; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01204003,0.0006761428,0.001362288,0.0004271411,0.000178857,0.0007088894,0.0006084777,0.0007481638,0.002095923],"category_scores_gemma":[0.009022394,0.0002585716,0.006407815,0.0004604009,0.000348899,0.0005013846,0.0008545475,0.001156905,0.000151511],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009364143,"about_ca_system_score_gemma":0.0006119183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002917786,"about_ca_topic_score_gemma":0.002976115,"domain_scores_codex":[0.9966809,0.002588114,0.0001220139,0.0002483199,0.0001972594,0.0001634018],"domain_scores_gemma":[0.9880656,0.00879164,0.001720293,0.0006040859,0.0003591523,0.0004592294],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2518074,0.002667018,0.5455188,0.00332952,0.04835539,0.00140854,0.0004519935,0.08743041,0.00305941,0.001295284,0.002734293,0.05194206],"study_design_scores_gemma":[0.01995011,0.04092108,0.8015843,0.0006422331,0.04188232,0.001183933,0.0003714006,0.08522093,0.001486888,0.002480148,0.00409579,0.000180749],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934924,0.003685765,0.0006503831,0.0002023281,0.00001550688,0.0001088323,0.001438648,0.000009024561,0.0003970696],"genre_scores_gemma":[0.9972968,0.0005839674,0.0002424851,0.00009491898,0.00001309579,0.00004971418,0.001572099,0.000003754104,0.0001432331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01204003,"threshold_uncertainty_score":0.06367457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1472720692724658,"score_gpt":0.4858071898261185,"score_spread":0.3385351205536527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}