{"id":"W3159540282","doi":"10.1093/ehjqcco/qcab031","title":"Health impact of tafamidis in transthyretin amyloid cardiomyopathy patients: an analysis from the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and the open-label long-term extension studies","year":2021,"lang":"en","type":"article","venue":"European Heart Journal - Quality of Care and Clinical Outcomes","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"EVERSANA (Canada)","funders":"Pfizer","keywords":"Medicine; Internal medicine; Confidence interval; Cohort; Transthyretin; Cardiomyopathy; Oncology; Cardiology; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00990089,0.000438049,0.00296611,0.0001025571,0.0002129011,0.0001165415,0.0005501187,0.0001868383,0.00001052222],"category_scores_gemma":[0.003285033,0.0002570121,0.001929441,0.0003650842,0.0009250864,0.00004619143,0.0003674723,0.000664814,7.965656e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006735913,"about_ca_system_score_gemma":0.0003209662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001070494,"about_ca_topic_score_gemma":0.00316483,"domain_scores_codex":[0.980914,0.01377488,0.003559171,0.0008443385,0.0004979093,0.000409713],"domain_scores_gemma":[0.9942021,0.003090411,0.001050135,0.0009285673,0.0004272538,0.0003015125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009684194,0.001149175,0.9708909,0.00004135757,0.002370274,0.00003393163,0.001729393,0.00002033251,0.00003322563,0.0000065417,0.00007573854,0.0139649],"study_design_scores_gemma":[0.04807094,0.003458185,0.9449555,0.0001311741,0.0007587824,0.00000723208,0.002214215,0.000003109208,0.00003699831,0.0000185079,0.00008966168,0.0002556458],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9771019,0.01930798,0.0000258349,0.002181328,0.0002994562,0.0007818567,0.0002634684,0.000005793683,0.00003233348],"genre_scores_gemma":[0.9648758,0.03316262,0.000210558,0.001303644,0.0002109767,0.00001116293,0.0001791578,0.00003736792,0.000008689915],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03838675,"threshold_uncertainty_score":0.9999882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1472720692724658,"score_gpt":0.4858071898261185,"score_spread":0.3385351205536527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}