{"id":"W3159566552","doi":"10.2147/ijn.s301851","title":"Nanoparticles of Chitosan/Poly(D,L-Lactide-Co-Glycolide) Enhanced the Immune Responses of Haemonchus contortus HCA59 Antigen in Model Mice","year":2021,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"Helminth infection and control","field":"Veterinary","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China; McGill University","keywords":"PLGA; Immune system; Antigen; Adjuvant; CD8; Chitosan; Biology; Molecular biology; Immunology; Chemistry; In vitro; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001210672,0.0004911218,0.0002301417,0.0003204825,0.000101978,0.0001362213,0.0001550051,0.0004790675,0.000608589],"category_scores_gemma":[0.00009340396,0.0001480343,0.0002756192,0.00008763861,0.0001981627,0.0002070926,0.0001269351,0.0004951707,0.0001395038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002699997,"about_ca_system_score_gemma":0.0001593051,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006883706,"about_ca_topic_score_gemma":0.001052451,"domain_scores_codex":[0.9998945,0.00001054194,0.000007183417,0.00002230227,0.00003400727,0.00003151884],"domain_scores_gemma":[0.9999235,0.000008362399,0.00002422484,0.000004523523,0.00001380998,0.00002557638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001304437,0.00006775817,0.00004999749,0.00004348728,0.000004131191,0.00002208882,0.000005998935,0.00006144486,0.9988097,0.00002124802,0.00002897347,0.0007546589],"study_design_scores_gemma":[0.00005941703,0.001963324,0.001949337,0.00001039155,0.00003901267,0.0001199241,0.00001185304,0.001133708,0.9936543,0.0000200065,0.001033556,0.0000052817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942818,0.001642439,0.002198793,0.000164955,0.00006739834,0.00008041455,0.0001609882,0.0001042986,0.001298951],"genre_scores_gemma":[0.9927065,0.0009938957,0.002872209,0.00009944555,0.00002645164,0.00009802411,0.0002197667,0.0000168703,0.002966746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006883706,"threshold_uncertainty_score":0.002035975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04063740391219004,"score_gpt":0.3609812351582759,"score_spread":0.3203438312460858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}