{"id":"W3159572711","doi":"10.1002/cbic.202100087","title":"Functional Nucleic Acids Under Unusual Conditions","year":2021,"lang":"en","type":"review","venue":"ChemBioChem","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Deoxyribozyme; Ribozyme; Nucleic acid; Aptamer; Ligase ribozyme; RNA; Computational biology; Nucleic acid structure; Chemistry; Riboswitch; G-quadruplex; Biology; Combinatorial chemistry; Biochemistry; Nanotechnology; DNA; Molecular biology; Non-coding RNA; Materials science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003102474,0.0008744606,0.0006365103,0.0008032381,0.0003039287,0.0008053178,0.0005560987,0.0009560014,0.003455342],"category_scores_gemma":[0.0003084136,0.0002846563,0.000308224,0.0009051231,0.0004799466,0.001182697,0.0007314605,0.001576698,0.003525628],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005361979,"about_ca_system_score_gemma":0.0005671381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005947282,"about_ca_topic_score_gemma":0.0008237793,"domain_scores_codex":[0.9997763,0.00002867561,0.00001673275,0.00004505673,0.00009496659,0.00003824397],"domain_scores_gemma":[0.9999392,0.00002062904,0.00001162672,0.000005718381,0.0000160264,0.000006798599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006703862,0.00008717673,0.0001897404,0.01956283,0.00008668941,0.0008158245,0.0002145512,0.001225546,0.1264288,0.04800394,0.02847806,0.7748398],"study_design_scores_gemma":[0.000007080799,0.00005389483,0.0001685366,0.0005277658,0.00001986122,0.0009507906,0.00002679656,0.0001026585,0.01906305,0.002036612,0.977027,0.0000160294],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00304819,0.9589595,0.003644745,0.0004862847,0.000912044,0.00004648143,0.0001450256,0.00008239529,0.03267535],"genre_scores_gemma":[0.01903633,0.9633837,0.002762155,0.0006326552,0.0002762802,0.00009379828,0.0002517002,0.0000192223,0.01354406],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003455342,"threshold_uncertainty_score":0.01155925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03674300835624542,"score_gpt":0.3383626902511376,"score_spread":0.3016196818948922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}