{"id":"W3159637870","doi":"10.1242/dev.192054","title":"MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus","year":2021,"lang":"en","type":"article","venue":"Development","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Université de Sherbrooke","funders":"European Social Fund; Medical Research Council; National Institutes of Health; Neuron Nadační Fond Na Podporu Vědy; Masarykova Univerzita; KWF Kankerbestrijding; Vetenskapsrådet; Karolinska Institutet; Universiteit van Amsterdam; Grantová Agentura České Republiky; Cancerfonden; New York Stem Cell Foundation; Stiftelsen för Strategisk Forskning; National Institute of Neurological Disorders and Stroke; National Institute for Health and Care Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Wellcome Trust; Eunice Kennedy Shriver National Institute of Child Health and Human Development; NIHR Cambridge Biomedical Research Centre; Boston Children's Hospital; European Commission; Stiftelsen för Strategisk Forskning; Hjärnfonden","keywords":"Choroid plexus; Wnt signaling pathway; Biology; WNT5A; Cell biology; Fourth ventricle; Cerebrospinal fluid; Ventricle; Morphogenesis; Epithelium; Beta-catenin; Anatomy; Cerebral ventricle; Embryonic stem cell; Internal medicine; Signal transduction; Endocrinology; Gene; Central nervous system; Genetics; Neuroscience; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009475483,0.0003834548,0.0002301988,0.0004508424,0.0002642247,0.0004123201,0.0001855346,0.0002509642,0.001291498],"category_scores_gemma":[0.0001225469,0.0002605921,0.0002672014,0.0001272115,0.000344364,0.000280382,0.0003719252,0.0005493917,0.0004893291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007394098,"about_ca_system_score_gemma":0.0005188736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002875456,"about_ca_topic_score_gemma":0.003710187,"domain_scores_codex":[0.9998258,0.00002031734,0.0000112012,0.00005235382,0.00004554374,0.00004486644],"domain_scores_gemma":[0.9998939,0.000005406292,0.00003767466,0.000005104997,0.00001386272,0.00004409233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007247036,0.000004041416,0.0007203034,0.00002329904,0.000004336154,0.00009484287,0.00002443673,0.00005210657,0.9972587,0.0003854297,0.00006316409,0.00129684],"study_design_scores_gemma":[0.00001661744,0.0000758701,0.05755,0.00002001989,0.00001845075,0.00027935,0.0001045839,0.001391314,0.9341159,0.0002120688,0.006206609,0.000009255175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736559,0.00730611,0.008924008,0.0002290203,0.00006901936,0.00004520201,0.001232717,0.0003566899,0.008181289],"genre_scores_gemma":[0.987854,0.001482727,0.002103975,0.00005580294,0.000009423951,0.00003032322,0.0005473164,0.00005049227,0.007866005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002875456,"threshold_uncertainty_score":0.005717397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01440446299347284,"score_gpt":0.2448521566675116,"score_spread":0.2304476936740388,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}