{"id":"W3159724798","doi":"10.15252/embj.2020105770","title":"Wnt and Src signals converge on YAP‐TEAD to drive intestinal regeneration","year":2021,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Beatson Institute for Cancer Research; Medical Research Council; Australian National University; Wellcome Trust; Francis Crick Institute; Cancer Research UK","keywords":"Biology; Wnt signaling pathway; Regeneration (biology); Cell biology; Genetics; Computational biology; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004175738,0.0001123579,0.0001051545,0.00002669653,0.0002320816,0.00008273745,0.0001167878,0.00005354767,0.00007303631],"category_scores_gemma":[0.0002036349,0.00008001627,0.00005513678,0.00006344303,0.00003799194,0.000002904799,0.00006024305,0.0001955857,0.00003208454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001279087,"about_ca_system_score_gemma":0.0001159525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003206521,"about_ca_topic_score_gemma":0.000009598415,"domain_scores_codex":[0.9991413,0.0001693512,0.0001749813,0.0001886044,0.0001471469,0.0001785898],"domain_scores_gemma":[0.9994348,0.00002814312,0.00006994771,0.0001689043,0.0001664286,0.0001317601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007683113,0.00002772218,0.0001381468,0.000002864316,0.00003210854,0.00003959774,0.0001968663,0.0004672741,0.9945807,0.0001856509,0.001848772,0.002403424],"study_design_scores_gemma":[0.0003127223,0.0005574067,0.0002717965,0.00005462229,0.00002088159,0.000821579,0.0001762622,0.0001127294,0.9875513,0.0005631881,0.009424408,0.0001331394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929352,0.0006312371,0.003143128,0.00216392,0.0002311263,0.00005874794,0.000005228627,0.000005970578,0.0008254662],"genre_scores_gemma":[0.9952438,0.0001362124,0.0005450617,0.00164798,0.0008171508,0.000004040076,0.00001570532,0.00001356086,0.001576428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007575637,"threshold_uncertainty_score":0.3262969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01561212236530923,"score_gpt":0.2564794742959209,"score_spread":0.2408673519306117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}