{"id":"W3159733223","doi":"10.3390/cancers13092088","title":"Associations between Genetically Predicted Circulating Protein Concentrations and Endometrial Cancer Risk","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Health Services","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute on Aging; Cancer Research UK; University of Cambridge; National Health and Medical Research Council; Canadian Institutes of Health Research; Ovarian Cancer Research Fund; U.S. Department of Health and Human Services; National Institutes of Health; Ministerio de Economía y Competitividad; Wellcome Trust; Roswell Park Cancer Institute","keywords":"Endometrial cancer; Biology; ABO blood group system; Genome-wide association study; Odds ratio; Immunology; Internal medicine; Cancer; Endocrinology; Genetics; Single-nucleotide polymorphism; Medicine; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001260434,0.0003961822,0.0002705839,0.0004977491,0.0002341387,0.0004426649,0.0003415893,0.0006646186,0.001085013],"category_scores_gemma":[0.00706804,0.0002562257,0.0004544131,0.0004710451,0.0003323554,0.000213665,0.0004022856,0.0007443335,0.0001244865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001815752,"about_ca_system_score_gemma":0.0001525155,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001050786,"about_ca_topic_score_gemma":0.0007901434,"domain_scores_codex":[0.9988889,0.0004690696,0.00007763774,0.0003146419,0.0001667,0.00008308004],"domain_scores_gemma":[0.9964716,0.001711282,0.001050655,0.000456113,0.0001593928,0.0001508292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003210945,0.00002593745,0.9929236,0.00001260453,0.0002957161,0.0001820414,0.00003544857,0.0004614848,0.003486604,0.0001083504,0.00006194528,0.00208523],"study_design_scores_gemma":[0.00001546742,0.0001005365,0.9959656,0.00000417954,0.0001031621,0.0006522277,0.00002204467,0.002070322,0.0006685444,0.0002377623,0.000151737,0.000008320836],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982027,0.000296809,0.0009802276,0.00006268666,0.000008680339,0.00000326967,0.0002280185,0.00001315269,0.0002044394],"genre_scores_gemma":[0.9990379,0.00006147407,0.0006190729,0.00001762833,0.000008505622,0.000004639813,0.0001617167,0.000003497732,0.00008560818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001260434,"threshold_uncertainty_score":0.006665885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798947630335241,"score_gpt":0.295059840744631,"score_spread":0.2770703644412786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}