{"id":"W3159770748","doi":"10.1016/j.bmcl.2021.128089","title":"Exploring boron applications in modern agriculture: A structure-activity relationship study of a novel series of multi-substitution benzoxaboroles for identification of potential fungicides","year":2021,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Insect Resistance and Genetics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Mitacs; Canada Research Chairs; Canadian Institute for Advanced Research","keywords":"Fungicide; Chemistry; Stereochemistry; Antifungal; Structure–activity relationship; Colletotrichum; Combinatorial chemistry; Biochemistry; Botany; In vitro; Biology; Microbiology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001019719,0.000125495,0.0001977974,0.00002716664,0.00004623333,0.00000462251,0.0001199997,0.00009315579,0.000001864296],"category_scores_gemma":[0.0001016242,0.0001218384,0.00005864798,0.0001923124,0.00008475834,0.00001264463,0.00003232141,0.00007471127,2.419654e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002582711,"about_ca_system_score_gemma":0.00007948983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002783774,"about_ca_topic_score_gemma":0.0001402785,"domain_scores_codex":[0.9990262,0.0000220606,0.0003891817,0.0002716429,0.0001718623,0.0001190928],"domain_scores_gemma":[0.9991947,0.00001555693,0.0002893925,0.0002729415,0.0001996744,0.00002771394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001158796,0.0003903729,0.004787312,0.0002819856,0.00005062511,6.643755e-7,0.0004058724,0.0009011254,0.9929297,0.00000934704,0.000004263281,0.0001228417],"study_design_scores_gemma":[0.0008790171,0.00004918866,0.08309138,0.00003224931,0.0000739911,0.000005913845,0.001645468,0.00007724122,0.9140319,0.000008101839,0.00001031013,0.00009522793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9711528,0.000485859,0.0278388,0.00007340225,0.00004002246,0.0002997367,0.0001037328,0.000003912039,0.000001766008],"genre_scores_gemma":[0.9988731,0.00004553576,0.0006723552,0.000007614744,0.00008835441,0.00005739446,0.0002343212,0.00001042529,0.0000108898],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0788978,"threshold_uncertainty_score":0.4968426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04174390633698547,"score_gpt":0.2605592254048065,"score_spread":0.2188153190678211,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}