{"id":"W3159808103","doi":"10.1002/mds.28596","title":"Concomitant Medication Usage with <scp>Levodopa‐Carbidopa</scp> Intestinal Gel: Results from the <scp>COSMOS</scp> Study","year":2021,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; Krembil Foundation; University of Toronto","funders":"Allergan; Pécsi Tudományegyetem; Sanofi; AbbVie; Ipsen; Teva Pharmaceutical Industries; National Research, Development and Innovation Office; H. Lundbeck A/S; Boston Scientific Corporation; Parkinson's Foundation; Pfizer","keywords":"Medicine; Carbidopa; Parkinson's disease; Levodopa; Dyskinesia; Internal medicine; Physical therapy; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004543626,0.0004475366,0.0004803617,0.00007844457,0.0002973579,0.00009641623,0.0002858745,0.00008398914,0.00006144761],"category_scores_gemma":[0.001166738,0.0003016984,0.0001484403,0.000432026,0.0001330999,0.0001178471,0.000169153,0.000325646,0.00008971365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002218102,"about_ca_system_score_gemma":0.000345663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109041,"about_ca_topic_score_gemma":0.001413475,"domain_scores_codex":[0.9966245,0.0002363647,0.0005581291,0.0009114692,0.001101361,0.0005682145],"domain_scores_gemma":[0.9972149,0.0009495285,0.000307666,0.001001228,0.0001805528,0.000346183],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003179486,0.01235734,0.8890003,0.00008740005,0.003700211,0.002008238,0.01120773,0.00009768466,0.003016009,0.0006106606,0.06150787,0.01608863],"study_design_scores_gemma":[0.02142062,0.002148893,0.8832778,0.0003451677,0.001520463,0.000007034092,0.04164835,0.0007416692,0.0035044,0.007075457,0.03818318,0.0001269766],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9858916,0.001227109,0.001051071,0.001907931,0.0002888633,0.001587804,0.000261679,0.0001563151,0.007627632],"genre_scores_gemma":[0.9914918,0.0002170608,0.000594894,0.004592544,0.0001437081,0.0002904837,0.000722905,0.00006976744,0.001876823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03044062,"threshold_uncertainty_score":0.9999435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01732203691368127,"score_gpt":0.2545828622806561,"score_spread":0.2372608253669748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}