{"id":"W3159903976","doi":"10.1210/jendso/bvab048.1391","title":"Phase 3 Study Evaluating Once Weekly Somatrogon Compared to Daily Genotropin in Japanese Patients With Pediatric Growth Hormone Deficiency (pGHD)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Sexual Differentiation and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"OPKO Health (Canada)","funders":"","keywords":"Confidence interval; Medicine; Clinical endpoint; Human growth hormone; Randomized controlled trial; Adverse effect; Growth hormone deficiency; Internal medicine; Hormone; Growth hormone; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631525,0.0001329329,0.0001879203,0.00002862759,0.00009915809,0.00003282855,0.000243265,0.00002546062,0.00000955617],"category_scores_gemma":[0.000210317,0.00009154915,0.0001498538,0.0003290339,0.00001873105,0.00001055534,0.0001417901,0.0001555739,0.000001400193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003826479,"about_ca_system_score_gemma":0.0001446645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000169266,"about_ca_topic_score_gemma":0.00001999811,"domain_scores_codex":[0.9986748,0.000149524,0.0003663922,0.0001881454,0.0004093692,0.0002118369],"domain_scores_gemma":[0.9990624,0.00001841818,0.0002519389,0.0002023295,0.0003875711,0.00007730374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008110681,0.008341002,0.8347245,0.00005289369,0.0002104065,0.00001483574,0.005972921,0.001595751,0.1413404,0.00000537828,0.006119656,0.0008112229],"study_design_scores_gemma":[0.0259805,0.005225425,0.9472054,0.00002091663,0.0002101137,0.00002935487,0.01525259,0.000226708,0.005318433,0.00002394821,0.0001570845,0.0003494796],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985892,0.0005748954,0.0001542745,0.0002475772,0.0001494704,0.0002342405,0.000007190587,0.000003204139,0.0000399188],"genre_scores_gemma":[0.9987402,0.00004299852,0.0006531837,0.0003015011,0.0001266877,0.000005524199,0.00001891519,0.00001380246,0.00009718976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.136022,"threshold_uncertainty_score":0.3733266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552892224758939,"score_gpt":0.3035517525973199,"score_spread":0.2880228303497305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}