{"id":"W3159903976","doi":"10.1210/jendso/bvab048.1391","title":"Phase 3 Study Evaluating Once Weekly Somatrogon Compared to Daily Genotropin in Japanese Patients With Pediatric Growth Hormone Deficiency (pGHD)","year":2021,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Sexual Differentiation and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"OPKO Health (Canada)","funders":"","keywords":"Confidence interval; Medicine; Clinical endpoint; Human growth hormone; Randomized controlled trial; Adverse effect; Growth hormone deficiency; Internal medicine; Hormone; Growth hormone; Pediatrics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009535903,0.001081376,0.001972847,0.0003077002,0.0003669717,0.0004594294,0.0006151587,0.00083102,0.003136357],"category_scores_gemma":[0.0005683286,0.0004429397,0.001083738,0.0003508319,0.0007807855,0.0005191416,0.0002857353,0.001938073,0.0003799309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007836146,"about_ca_system_score_gemma":0.001598526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001575432,"about_ca_topic_score_gemma":0.003370994,"domain_scores_codex":[0.9997113,0.0001399172,0.00001597137,0.00005056486,0.00002818938,0.00005394251],"domain_scores_gemma":[0.999431,0.00008943661,0.0001127407,0.0000441146,0.00004252854,0.0002801824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8952252,0.04168981,0.003937332,0.0005675037,0.001105112,0.0001267766,0.0001884845,0.000877814,0.02210145,0.0001141671,0.0009776453,0.03308887],"study_design_scores_gemma":[0.5390428,0.4483224,0.009605838,0.00001852383,0.0003930746,0.00009182796,0.00005364477,0.0004646583,0.0012252,0.00006104624,0.000703065,0.00001808988],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967927,0.0009553657,0.0002141424,0.0001427308,0.00006563029,0.001039674,0.0002826426,0.00003578941,0.0004712794],"genre_scores_gemma":[0.993696,0.0009361962,0.001243742,0.0004395478,0.0001019315,0.00189655,0.0005948504,0.00001503442,0.001076168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003136357,"threshold_uncertainty_score":0.01049221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01552892224758939,"score_gpt":0.3035517525973199,"score_spread":0.2880228303497305,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}