{"id":"W3159954488","doi":"10.2460/ajvr.82.5.405","title":"Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs","year":2021,"lang":"en","type":"article","venue":"American Journal of Veterinary Research","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Altasciences (Canada); Canadian Science Centre for Human and Animal Health","funders":"Health Canada","keywords":"Medicine; Cannabidiol; Placebo; Pharmacokinetics; Adverse effect; Oral administration; Randomized controlled trial; Anesthesia; Route of administration; Pharmacology; Internal medicine; Cannabis; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003229642,0.001754978,0.003844128,0.000752546,0.000619613,0.0009605396,0.001648172,0.002198964,0.002506988],"category_scores_gemma":[0.004022977,0.001197857,0.001072802,0.0005818526,0.002305184,0.00129115,0.0004873981,0.002132539,0.0006044691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001095083,"about_ca_system_score_gemma":0.001617771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005884296,"about_ca_topic_score_gemma":0.001130459,"domain_scores_codex":[0.9973586,0.001229334,0.0002105496,0.0005730658,0.0003735047,0.0002549143],"domain_scores_gemma":[0.9958202,0.0006677749,0.001735602,0.0006192242,0.0005179193,0.0006392681],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9064836,0.04663833,0.0007746317,0.0004183528,0.0004188248,0.00005096611,0.00008378005,0.0004209989,0.03201734,0.00007246371,0.000372427,0.01224829],"study_design_scores_gemma":[0.2859716,0.7001911,0.002829961,0.00002699039,0.0004446103,0.00006685909,0.00005067807,0.0008301857,0.00853767,0.00008850949,0.0009289542,0.0000329583],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927573,0.0008529637,0.0009683436,0.0001181418,0.0001797946,0.004178006,0.0004889136,0.00008888797,0.0003675709],"genre_scores_gemma":[0.9800633,0.001413466,0.005803662,0.0003575563,0.0004854652,0.008998515,0.0008396922,0.00004877839,0.001989511],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003844128,"threshold_uncertainty_score":0.01708019,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09354816234434087,"score_gpt":0.458400871816669,"score_spread":0.3648527094723281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}