{"id":"W3159954488","doi":"10.2460/ajvr.82.5.405","title":"Randomized, placebo-controlled, 28-day safety and pharmacokinetics evaluation of repeated oral cannabidiol administration in healthy dogs","year":2021,"lang":"en","type":"article","venue":"American Journal of Veterinary Research","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"Altasciences (Canada); Canadian Science Centre for Human and Animal Health","funders":"Health Canada","keywords":"Medicine; Cannabidiol; Placebo; Pharmacokinetics; Adverse effect; Oral administration; Randomized controlled trial; Anesthesia; Route of administration; Pharmacology; Internal medicine; Cannabis; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0238189,0.0001603767,0.001331003,0.0006860687,0.0000856246,0.00003894633,0.0001404743,0.00006411593,0.0002519665],"category_scores_gemma":[0.003457446,0.0001280587,0.0002218994,0.001087368,0.0008546388,0.0001200259,0.00009676076,0.0008887778,0.000001488671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000374268,"about_ca_system_score_gemma":0.003467675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003063151,"about_ca_topic_score_gemma":0.00004092983,"domain_scores_codex":[0.9897831,0.005989702,0.001260079,0.0002878373,0.002211468,0.0004678146],"domain_scores_gemma":[0.9948021,0.0004062592,0.0004653628,0.0002813255,0.003664181,0.0003807909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8521652,0.0005208075,0.0009947459,0.0001625665,0.0002587943,0.00106963,0.0006957575,0.00009324026,0.02573825,0.00002902186,0.001244479,0.1170275],"study_design_scores_gemma":[0.900957,0.03331826,0.02759613,0.0006682765,0.0004603577,0.006157959,0.004265424,0.01232467,0.00393644,0.000131308,0.009863603,0.0003205527],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818016,0.002776585,0.00005179875,0.01329941,0.00009885702,0.001210907,0.000009849893,0.00000412682,0.0007468386],"genre_scores_gemma":[0.9954852,0.003356877,0.0002452625,0.00009922447,0.0001424464,0.00006330603,0.00001273972,0.00002333091,0.0005715969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1167069,"threshold_uncertainty_score":0.8255202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09354816234434087,"score_gpt":0.458400871816669,"score_spread":0.3648527094723281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}