{"id":"W3160066513","doi":"10.1038/s41379-021-00818-6","title":"Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes","year":2021,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Urologic and reproductive health conditions","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"Brigham and Women's Hospital","keywords":"Stromal cell; Biology; Pathology; Prostate; Sarcoma; Mesenchymal stem cell; Cancer research; Cancer; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004273527,0.0003563139,0.0003736748,0.002221353,0.0004962033,0.0009588087,0.0004020304,0.0006299957,0.002468578],"category_scores_gemma":[0.0008955123,0.000210761,0.000340925,0.0007347584,0.0005975797,0.0006808128,0.0005396509,0.0004516013,0.0008126062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003418625,"about_ca_system_score_gemma":0.0003413238,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001602129,"about_ca_topic_score_gemma":0.002541146,"domain_scores_codex":[0.9996812,0.00002497671,0.00003083338,0.00007465448,0.00009046011,0.00009778402],"domain_scores_gemma":[0.9993801,0.0001656961,0.00007603766,0.0001458136,0.0001127176,0.0001196646],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008811524,0.00004964867,0.1507121,0.00020474,0.0001014289,0.0352008,0.000729059,0.000661499,0.7624108,0.0008089407,0.0005812507,0.04765869],"study_design_scores_gemma":[0.00003494913,0.0003316056,0.3729532,0.00006566826,0.0004166447,0.2836438,0.002569094,0.007045547,0.3150863,0.001984279,0.01582534,0.00004369046],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880573,0.001861266,0.003654135,0.0002616974,0.00003075025,0.00004096713,0.0002618634,0.0001956719,0.005636368],"genre_scores_gemma":[0.9960449,0.0004944357,0.002117453,0.00006336464,0.00001876098,0.000007880741,0.0002617612,0.00003959658,0.0009517283],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002468578,"threshold_uncertainty_score":0.008258224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07062539781728172,"score_gpt":0.3888117364852353,"score_spread":0.3181863386679536,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}