{"id":"W3160239680","doi":"10.1016/j.bioelechem.2021.107842","title":"Interaction of LL-37 human cathelicidin peptide with a model microbial-like lipid membrane","year":2021,"lang":"en","type":"article","venue":"Bioelectrochemistry","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University","funders":"Narodowe Centrum Nauki","keywords":"Membrane; Cathelicidin; Biophysics; Phospholipid; Lipid bilayer; Chemistry; Peptide; Antimicrobial peptides; Cell membrane; Force spectroscopy; Biochemistry; Molecule; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148207,0.0002523929,0.000209969,0.0000908263,0.0001417817,0.0001891113,0.0001906633,0.000310622,0.0003526253],"category_scores_gemma":[0.000201602,0.00007663066,0.0002099031,0.000116004,0.0001350374,0.000244601,0.0002199603,0.000263405,0.0001464011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002666161,"about_ca_system_score_gemma":0.0001248356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003783539,"about_ca_topic_score_gemma":0.0002232922,"domain_scores_codex":[0.9998449,0.00003834337,0.00001033028,0.00003472443,0.00004529183,0.0000263108],"domain_scores_gemma":[0.9999373,0.00002034078,0.00001674414,0.000006328662,0.000009145338,0.00001012362],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004946709,0.000007927259,0.0001078407,0.00003272105,0.000005671432,0.00004367862,0.0000100726,0.0001130749,0.9991323,0.00003825686,0.00000905071,0.0004499411],"study_design_scores_gemma":[0.000005543392,0.0001445238,0.0007788806,0.000004725354,0.000008530064,0.0001115871,0.00002263375,0.0016115,0.9967282,0.00002639115,0.0005536668,0.000003748702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970221,0.0009860276,0.001514687,0.00004812059,0.00001188559,0.00001300351,0.00008859175,0.00001173585,0.0003039352],"genre_scores_gemma":[0.9967343,0.0006890456,0.002125432,0.00003064463,0.000004392582,0.00001744481,0.0001030736,0.000003469358,0.000292333],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003783539,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01091815774441946,"score_gpt":0.2290512221831364,"score_spread":0.218133064438717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}