{"id":"W3160364764","doi":"","title":"The Presynaptic Transmitter Release Site Within the Calcium Nanodomain: Calcium Channel and Synaptic Vesicle Tethering","year":2014,"lang":"en","type":"dissertation","venue":"TSpace","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Strong; National Science Foundation","keywords":"Tethering; Synaptic vesicle; Calcium; Biophysics; Chemistry; Active zone; Voltage-dependent calcium channel; Neurotransmission; Vesicle; Cell biology; Anatomy; Neuroscience; Biology; Biochemistry; Membrane; Receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007427252,0.0001710258,0.0001467438,0.0001739958,0.000258474,0.0002664217,0.0003277414,0.0003439577,0.001344262],"category_scores_gemma":[0.00007000582,0.0001015379,0.0001694061,0.000129886,0.0003064747,0.0003401881,0.0002129383,0.000436579,0.0005029342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005050496,"about_ca_system_score_gemma":0.0002745743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007181194,"about_ca_topic_score_gemma":0.001321874,"domain_scores_codex":[0.9999603,0.000002161785,0.000001641635,0.00001324822,0.0000134183,0.000009135229],"domain_scores_gemma":[0.9999744,0.000004487531,0.000005608637,0.000002498618,0.000004485609,0.000008499446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001598661,0.00004362061,0.0002585457,0.0001929509,0.000007086826,0.0002889917,0.00003330897,0.0002790389,0.9812618,0.006805511,0.000387687,0.01028156],"study_design_scores_gemma":[0.00005730579,0.0001803724,0.01900215,0.00005052711,0.00003200859,0.001456086,0.00008421511,0.003640071,0.9568668,0.003232792,0.01537774,0.00001993543],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9127958,0.0280431,0.01727168,0.001437292,0.0003593342,0.0001050612,0.0003234275,0.0001468301,0.03951761],"genre_scores_gemma":[0.9674501,0.006875141,0.003993705,0.0001353621,0.00004932856,0.00004653049,0.0002165152,0.00001806554,0.02121527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001344262,"threshold_uncertainty_score":0.004496992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02960575952256103,"score_gpt":0.2936268207337487,"score_spread":0.2640210612111877,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}