{"id":"W3160574226","doi":"10.3389/fimmu.2021.609543","title":"Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Key Research and Development Program of China; Natural Science Foundation of Jiangsu Province; Government of Jiangsu Province; Priority Academic Program Development of Jiangsu Higher Education Institutions; Yangzhou University; National Natural Science Foundation of China","keywords":"MDA5; Innate immune system; RIG-I; Biology; RNA silencing; Cell biology; Virology; Receptor; Immune system; Molecular biology; RNA; Gene; RNA interference; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013236,0.0002879935,0.0001554796,0.0002490629,0.0001313181,0.0002375666,0.0001236034,0.0003033222,0.001332641],"category_scores_gemma":[0.0001092171,0.0000949092,0.0005492354,0.000148679,0.0001561821,0.000230926,0.0001828104,0.0003894923,0.0005162745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188941,"about_ca_system_score_gemma":0.000105704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003998838,"about_ca_topic_score_gemma":0.0004695104,"domain_scores_codex":[0.9998562,0.00002237488,0.00001240636,0.0000408304,0.00002623463,0.0000418803],"domain_scores_gemma":[0.9999403,0.0000116958,0.00001746102,0.00001059749,0.000006796752,0.00001326981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004956076,0.000004637331,0.00041311,0.00001647498,0.000002555381,0.00006390628,0.000008296062,0.00002505493,0.9989539,0.00004008863,0.00001344328,0.0004088882],"study_design_scores_gemma":[0.000009349686,0.0003624688,0.03072666,0.00001456477,0.0000324073,0.001544504,0.0001285205,0.00183315,0.9607016,0.000102197,0.004532027,0.00001260066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880766,0.00177968,0.006496859,0.0001637964,0.00003004558,0.0000253928,0.001308208,0.00004766561,0.002071742],"genre_scores_gemma":[0.9900665,0.00065947,0.004332963,0.0001564032,0.00001022622,0.00002996445,0.002535579,0.00001799194,0.002190819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001332641,"threshold_uncertainty_score":0.004458129,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003825365645087441,"score_gpt":0.2094945575137777,"score_spread":0.2056691918686902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}