{"id":"W3160574226","doi":"10.3389/fimmu.2021.609543","title":"Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2","year":2021,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Key Research and Development Program of China; Natural Science Foundation of Jiangsu Province; Government of Jiangsu Province; Priority Academic Program Development of Jiangsu Higher Education Institutions; Yangzhou University; National Natural Science Foundation of China","keywords":"MDA5; Innate immune system; RIG-I; Biology; RNA silencing; Cell biology; Virology; Receptor; Immune system; Molecular biology; RNA; Gene; RNA interference; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003209744,0.0001715583,0.000748487,0.0004678344,0.00008422078,0.000004790109,0.0002178721,0.000334516,0.0005138671],"category_scores_gemma":[0.0001740541,0.0001372769,0.0001607426,0.0006969446,0.0007929141,0.00006613672,0.0001278611,0.0003037841,0.000007275416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005517787,"about_ca_system_score_gemma":0.00006852384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002321282,"about_ca_topic_score_gemma":0.00006369409,"domain_scores_codex":[0.9978805,0.0009312402,0.0005860769,0.0002932534,0.00003722826,0.0002716641],"domain_scores_gemma":[0.9988451,0.0002487848,0.0002937454,0.0004322052,0.0001713597,0.00000881753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002021051,0.0002100037,0.04585467,0.00001796684,0.005284397,0.000003355627,0.002016053,0.00001119396,0.9137798,0.0006177113,0.02260766,0.007576139],"study_design_scores_gemma":[0.002454147,0.0005801328,0.3684056,0.00008234715,0.0009878797,0.00005944194,0.004338997,0.00004736991,0.5895877,0.0002819821,0.03289615,0.0002781781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9485347,0.04715466,0.001034283,0.0006292015,0.001832302,0.0001823244,0.00007089618,0.00001434928,0.0005472549],"genre_scores_gemma":[0.9889544,0.001775524,0.0003207821,0.0001048617,0.000005122473,0.00001106026,0.0003990069,0.00001264384,0.008416625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.324192,"threshold_uncertainty_score":0.5626484,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003825365645087441,"score_gpt":0.2094945575137777,"score_spread":0.2056691918686902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}