{"id":"W3160625325","doi":"10.71781/12055","title":"Azacyclopeptide synthesis and their neuroprotective activity against Aβ toxicity","year":2018,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Université de Montréal","keywords":"Neuroprotection; Toxicity; Pharmacology; Medicine; Neuroscience; Biology; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006489727,0.0002098343,0.0001707374,0.0001881055,0.0001210262,0.0001810057,0.0001477966,0.0002847546,0.002139367],"category_scores_gemma":[0.0001028973,0.00008503569,0.0001345476,0.0001487524,0.0001127383,0.0002388706,0.0001111558,0.0002969786,0.0004665751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002197823,"about_ca_system_score_gemma":0.0001208043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000356743,"about_ca_topic_score_gemma":0.0004951028,"domain_scores_codex":[0.9999577,0.000006808457,0.000003865552,0.00001180019,0.00001004576,0.000009926816],"domain_scores_gemma":[0.9999614,0.000007956044,0.0000100089,0.000003976621,0.000007112231,0.000009511818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004949247,0.00005778594,0.0001393366,0.0001905014,0.000009346129,0.0002123837,0.00002621047,0.0004894181,0.9867007,0.0005862435,0.0001831847,0.01090996],"study_design_scores_gemma":[0.00006441688,0.001507014,0.001604149,0.00002066277,0.00001988655,0.0002983036,0.00001685149,0.0007871895,0.9834101,0.0002101944,0.01205121,0.0000100095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9579194,0.02686715,0.003364964,0.0002192695,0.0001042307,0.00008409446,0.000617787,0.00006107689,0.01076209],"genre_scores_gemma":[0.9746324,0.01217451,0.00304082,0.0001103672,0.00005420808,0.0000754268,0.0006813484,0.00001706703,0.009213835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002139367,"threshold_uncertainty_score":0.007156849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01415468663176048,"score_gpt":0.2704004655317304,"score_spread":0.2562457788999699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}