{"id":"W3160795068","doi":"10.1002/mds.28643","title":"Decoupling of Global Brain Activity and Cerebrospinal Fluid Flow in Parkinson's Disease Cognitive Decline","year":2021,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Cerebrospinal fluid and hydrocephalus","field":"Neuroscience","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Aging; National Center for Advancing Translational Sciences; Foundation for the National Institutes of Health","keywords":"Montreal Cognitive Assessment; Cerebrospinal fluid; Parkinson's disease; Cerebral blood flow; Medicine; Cardiology; Cognitive decline; Internal medicine; Neuroscience; Cognition; Psychology; Disease; Pathology; Dementia","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379637,0.000197039,0.0002444213,0.00004375677,0.0001027193,0.00004675771,0.0001224208,0.00004479076,0.0001119414],"category_scores_gemma":[0.0006267743,0.0002138766,0.00008377395,0.0004367121,0.0001509855,0.0001802181,0.0002456332,0.0001090926,0.00000541648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008256805,"about_ca_system_score_gemma":0.0001313686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001923938,"about_ca_topic_score_gemma":0.001562013,"domain_scores_codex":[0.9983964,0.00007808689,0.0002469593,0.0005783825,0.0003502977,0.0003498806],"domain_scores_gemma":[0.9994017,0.0001533957,0.0000745065,0.0001694608,0.00003524761,0.0001656406],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008185174,0.001113322,0.8843902,0.0001614834,0.00001689152,0.00008124797,0.0001597654,0.0005562648,0.08497083,0.001666674,0.000142917,0.02592192],"study_design_scores_gemma":[0.002544354,0.0001762236,0.9270728,0.0001250901,0.00002652844,8.33788e-7,0.0002201338,0.02129525,0.03104735,0.016877,0.0002957416,0.0003186537],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943915,0.0004371326,0.001199516,0.002910356,0.0001223307,0.0002591042,0.0001358226,0.00002664329,0.0005176174],"genre_scores_gemma":[0.9954972,0.0003752074,0.0000783193,0.003925459,0.00002366528,0.00002321799,0.000008470985,0.00001387287,0.00005455356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05392348,"threshold_uncertainty_score":0.8721635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01350752981191779,"score_gpt":0.2733752445965458,"score_spread":0.2598677147846281,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}