{"id":"W3160983506","doi":"10.1101/2021.05.11.443666","title":"Delayed DNA replication in haploid human embryonic stem cells","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; Rosetrees Trust; New York State Stem Cell Science","keywords":"Biology; Replication timing; Ploidy; Genetics; DNA replication; Chromosome; Control of chromosome duplication; Mitosis; DNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001279636,0.0001673043,0.0001726292,0.0003394323,0.0001104436,0.0003057638,0.0001030539,0.0001706144,0.001337217],"category_scores_gemma":[0.0002143179,0.0001717208,0.0001424096,0.0001712458,0.0001132171,0.0001797428,0.0002117561,0.0003075172,0.0003638699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003116071,"about_ca_system_score_gemma":0.0001491112,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005108349,"about_ca_topic_score_gemma":0.0006463638,"domain_scores_codex":[0.9998933,0.000009472916,0.00001284698,0.00004348976,0.00003059379,0.00001021908],"domain_scores_gemma":[0.9998322,0.00002543947,0.0000634541,0.00002943638,0.00002690282,0.00002261055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009435954,0.000004698737,0.001709688,0.00002831521,0.000004940669,0.00005400397,0.00002527007,0.0001255416,0.9964817,0.00008354779,0.00003583982,0.00135209],"study_design_scores_gemma":[0.00001100961,0.0001983551,0.04270744,0.000009438774,0.00001558517,0.0005912529,0.0000635118,0.0008895918,0.9526573,0.0002072336,0.002640663,0.000008659639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939675,0.001259408,0.00319381,0.00003327592,0.00001447055,0.00001484263,0.0009116074,0.00004790418,0.0005570889],"genre_scores_gemma":[0.9934379,0.0004652214,0.002562706,0.0000277328,0.000004237772,0.00002269955,0.001336895,0.00002341433,0.002119181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001337217,"threshold_uncertainty_score":0.004473507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01688868172523407,"score_gpt":0.2499757606541806,"score_spread":0.2330870789289465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}