{"id":"W3160997191","doi":"10.3389/fcell.2021.621779","title":"The Integral Role of RNA in Stress Granule Formation and Function","year":2021,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Fondation Brain Canada","keywords":"Stress granule; RNA; RNA-binding protein; Cell biology; Ribonucleoprotein; Biology; Neurodegeneration; Translation (biology); Messenger RNA; Genetics; Gene; Disease","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002026661,0.000134801,0.0003631765,0.00009385101,0.00004877272,0.00001293382,0.00008989266,0.0002213601,0.000001591054],"category_scores_gemma":[0.00002731157,0.00009171317,0.00004462281,0.0000933873,0.0001079746,0.000004047362,0.0001391723,0.0001509424,3.926027e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002952216,"about_ca_system_score_gemma":0.0001049736,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003924943,"about_ca_topic_score_gemma":0.0001583582,"domain_scores_codex":[0.9991392,0.0001281432,0.0002921317,0.0002143967,0.00003892831,0.0001872226],"domain_scores_gemma":[0.9997734,0.00002246226,0.00008241725,0.00007265876,0.00001624204,0.0000328341],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002959867,0.00001558406,0.002063256,0.000522148,0.00002459425,0.000001190759,0.00003714356,9.624841e-8,0.00281193,0.00001894432,0.000398172,0.9940773],"study_design_scores_gemma":[0.0004666141,0.0001647173,0.0002069636,0.0007865198,0.00002047119,0.00001826712,0.001960931,0.00002686085,0.006379502,0.0001797506,0.9895615,0.0002278754],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02331192,0.9757355,0.000164839,0.000004338065,0.0001285867,0.0001898514,0.00001714273,0.000001133796,0.0004466829],"genre_scores_gemma":[0.003558724,0.9951241,0.0005985178,0.000007944879,0.00001834677,0.00003428758,0.0004316036,0.000007034513,0.0002194366],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9938495,"threshold_uncertainty_score":0.3739955,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021791005493581,"score_gpt":0.2553127238987234,"score_spread":0.2450948138437876,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}