{"id":"W3161152175","doi":"10.1042/cs20200963","title":"Adventitial recruitment of Lyve-1− macrophages drives aortic aneurysm in an angiotensin-2-based murine model","year":2021,"lang":"en","type":"article","venue":"Clinical Science","topic":"Aortic aneurysm repair treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"","keywords":"Macrophage; CCR2; Inflammation; Angiotensin II; Medicine; Abdominal aortic aneurysm; Monocyte; Aortic aneurysm; Aorta; CX3CR1; Pathology; Receptor; Immunology; Chemokine; Aneurysm; Internal medicine; Chemokine receptor; Biology; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008479567,0.001218848,0.0006164417,0.001275847,0.0005262184,0.0007359395,0.0008365338,0.001296845,0.002372238],"category_scores_gemma":[0.0002182061,0.0007490541,0.0007008407,0.0003427192,0.0007895909,0.0006936665,0.0004728948,0.002134146,0.0009796274],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005489254,"about_ca_system_score_gemma":0.0003643177,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003571555,"about_ca_topic_score_gemma":0.0008588241,"domain_scores_codex":[0.9992906,0.0001309147,0.00009066715,0.0001726477,0.0001651174,0.0001500234],"domain_scores_gemma":[0.9991626,0.00007747334,0.0003395922,0.00009678674,0.00004661476,0.0002770424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007332253,0.0007112891,0.000315178,0.00008988424,0.00001244414,0.0002145675,0.00007284978,0.000164466,0.9963657,0.0003509053,0.00008902738,0.0008805721],"study_design_scores_gemma":[0.0003950281,0.006706201,0.007554249,0.0001028817,0.0001067493,0.002005673,0.0002221195,0.004649788,0.9718169,0.0003181669,0.006082343,0.00003993306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910948,0.0009917504,0.004905675,0.0002712412,0.0001436531,0.0002160307,0.0007502441,0.0002355236,0.001390996],"genre_scores_gemma":[0.9737763,0.001546547,0.01100712,0.0002190838,0.00009451313,0.000534243,0.0009938766,0.0001059216,0.01172232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002372238,"threshold_uncertainty_score":0.007935941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1190453974982847,"score_gpt":0.4363741668505264,"score_spread":0.3173287693522417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}