{"id":"W3161170556","doi":"10.1128/jvi.02425-20","title":"Selective BCL-X <sub>L</sub> Antagonists Eliminate Infected Cells from a Primary-Cell Model of HIV Latency but Not from <i>Ex Vivo</i> Reservoirs","year":2021,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Maple Leaf Medical Clinic","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Biology; Ex vivo; Ionomycin; Viremia; Immunology; Virology; In vivo; In vitro; Human immunodeficiency virus (HIV); Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001783403,0.0003633822,0.0005088554,0.0002232811,0.0002488386,0.0006431928,0.0004054661,0.0003292531,0.003317538],"category_scores_gemma":[0.0001457274,0.0001736718,0.0002268112,0.0001157357,0.0002997784,0.0003743366,0.0001416324,0.001577843,0.001065181],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002983385,"about_ca_system_score_gemma":0.0003160477,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006114498,"about_ca_topic_score_gemma":0.00148459,"domain_scores_codex":[0.9998115,0.00002544203,0.0000116613,0.00002839609,0.00004316504,0.00007987231],"domain_scores_gemma":[0.9998103,0.00005097179,0.00003184408,0.0000272978,0.00002057289,0.0000590323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004726897,0.0002378769,0.0002593471,0.00005847184,0.00001062773,0.00005918632,0.00003837999,0.0001225707,0.9938642,0.0004884665,0.000639411,0.003748731],"study_design_scores_gemma":[0.00006771438,0.001199523,0.001299243,0.00001024171,0.0000198237,0.000296902,0.00004702585,0.001319714,0.9923544,0.0001389435,0.003241723,0.000004823563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9818943,0.003024484,0.005917971,0.0005290023,0.0002314536,0.00009642184,0.000832723,0.0003994787,0.007074153],"genre_scores_gemma":[0.9876468,0.00139807,0.002979875,0.0001923602,0.00004575103,0.00006128403,0.0007051217,0.0000826618,0.006887964],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003317538,"threshold_uncertainty_score":0.01109827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01045338284965581,"score_gpt":0.2219750313881654,"score_spread":0.2115216485385096,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}