{"id":"W3161230983","doi":"10.1128/jvi.02311-20","title":"Differential Inhibition of HIV Replication by the 12 Interferon Alpha Subtypes","year":2021,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"Agence Nationale de Recherches sur le Sida et les Hépatites Virales","keywords":"Biology; Viral replication; Virus; Interferon; SAMHD1; Virology; Alpha interferon; Reverse transcriptase; Gene; RNA; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003168046,0.0002310471,0.0003070213,0.0001795383,0.00009223114,0.0003229518,0.0001806269,0.0002275685,0.000720509],"category_scores_gemma":[0.0002826845,0.0001315413,0.0002717763,0.0001109892,0.0001671635,0.0001511633,0.0001756947,0.0004854713,0.0002390918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001767495,"about_ca_system_score_gemma":0.0001826886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002412358,"about_ca_topic_score_gemma":0.0003857866,"domain_scores_codex":[0.9997279,0.0000849696,0.00002473334,0.00003109465,0.00004482095,0.00008636415],"domain_scores_gemma":[0.999854,0.00005759303,0.00001782147,0.00002568322,0.0000185036,0.00002633486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005015399,0.00004851049,0.00051709,0.00003800449,0.000005333236,0.00001801071,0.00001405855,0.00009100879,0.9923482,0.0001000972,0.00002093901,0.006297232],"study_design_scores_gemma":[0.00005169247,0.001827677,0.008532749,0.00002147944,0.00002807444,0.0001679217,0.00004781087,0.0009112703,0.9859931,0.00009814158,0.002314621,0.000005345453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933777,0.002728111,0.001487287,0.00004392266,0.00002967775,0.00004155897,0.0001174565,0.00002425269,0.002150036],"genre_scores_gemma":[0.9948332,0.001243922,0.001858297,0.00004153152,0.00001796067,0.00004039764,0.0001645216,0.00001249979,0.001787679],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000720509,"threshold_uncertainty_score":0.002410293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337573762355579,"score_gpt":0.264987192533078,"score_spread":0.2516114549095222,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}