{"id":"W3161335586","doi":"10.1016/j.ebiom.2021.103360","title":"Genetics and therapy for pediatric eye diseases","year":2021,"lang":"en","type":"review","venue":"EBioMedicine","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Eye Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Alberta","keywords":"Medicine; Blinding; Coloboma; Childhood blindness; Bioinformatics; Biology; Genetics; Clinical trial; Ophthalmology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007919811,0.0002647092,0.000611886,0.00008325312,0.00004977535,0.00001658853,0.000124726,0.0001976405,0.00002004489],"category_scores_gemma":[0.00006281451,0.0001952796,0.0001814899,0.0001410608,0.00006465755,7.601029e-7,0.00007188063,0.00005391669,0.000002491521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005295411,"about_ca_system_score_gemma":0.0002329204,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.175572e-7,"about_ca_topic_score_gemma":3.17701e-7,"domain_scores_codex":[0.9990122,0.0000340138,0.0002643529,0.0003948882,0.0001011867,0.0001933753],"domain_scores_gemma":[0.999481,0.00002773344,0.000112698,0.0002179921,0.00005506376,0.0001054911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001140682,0.00003780762,0.0003464604,0.003023122,0.0001116841,0.000003755725,0.000006076269,1.712488e-8,0.00001786492,0.000005398377,0.01726652,0.9791699],"study_design_scores_gemma":[0.0004951672,0.0002322227,0.00009888093,0.0003545076,0.0003184222,0.00000631019,0.00000851068,2.94472e-7,0.000007469656,0.000012223,0.9982312,0.0002347365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002083662,0.9986524,0.0001187732,0.00005565004,0.0002578641,0.0005344509,0.00006833372,0.000007559297,0.0000966298],"genre_scores_gemma":[0.00001283618,0.9942517,0.0003143022,0.0001267421,0.001085878,0.0001134405,0.002872834,0.00004093052,0.001181396],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9809647,"threshold_uncertainty_score":0.7963272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167954327055013,"score_gpt":0.3377955310286046,"score_spread":0.3161159877580545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}