{"id":"W3161335586","doi":"10.1016/j.ebiom.2021.103360","title":"Genetics and therapy for pediatric eye diseases","year":2021,"lang":"en","type":"review","venue":"EBioMedicine","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Eye Institute; Canadian Institutes of Health Research; National Institutes of Health; University of Alberta","keywords":"Medicine; Blinding; Coloboma; Childhood blindness; Bioinformatics; Biology; Genetics; Clinical trial; Ophthalmology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004257943,0.0008069501,0.0008522682,0.001681146,0.0002213037,0.0006904911,0.0006945099,0.001061785,0.004438765],"category_scores_gemma":[0.0005243891,0.0001708742,0.0004459509,0.0009882442,0.0003806456,0.0007566661,0.0007236597,0.001927211,0.002269357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005014534,"about_ca_system_score_gemma":0.0005180661,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004764725,"about_ca_topic_score_gemma":0.0009281328,"domain_scores_codex":[0.9998534,0.00002990394,0.00001848377,0.00002345173,0.00005958297,0.00001514672],"domain_scores_gemma":[0.9998456,0.00008135037,0.00002071875,0.000006615116,0.00003047237,0.00001508576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004941222,0.00007392837,0.0001114103,0.006463428,0.00007045003,0.0004078309,0.00003820408,0.0003695606,0.002241711,0.00544815,0.04162966,0.9430962],"study_design_scores_gemma":[0.00001659457,0.0000502169,0.0004302538,0.00225198,0.00006890681,0.002029259,0.00002190837,0.00008731238,0.0005224915,0.002421816,0.9920889,0.00001034991],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009837824,0.9976666,0.0002526725,0.0002836471,0.0002882266,0.000004500449,0.00001443145,0.0000128763,0.0013787],"genre_scores_gemma":[0.0007114108,0.9972544,0.0003659961,0.0002691493,0.000253457,0.000009733324,0.00003709186,0.000003393344,0.001095333],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004438765,"threshold_uncertainty_score":0.01484913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02167954327055013,"score_gpt":0.3377955310286046,"score_spread":0.3161159877580545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}