{"id":"W3161474571","doi":"10.1111/wrr.12928","title":"Biomimetic analyses of interactions between macrophages and palmar fascia myofibroblasts derived from Dupuytren's disease reveal distinct inflammatory cytokine responses","year":2021,"lang":"en","type":"article","venue":"Wound Repair and Regeneration","topic":"Dupuytren's Contracture and Treatments","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hand and Upper Limb Clinic; Lawson Health Research Institute; Western University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research","keywords":"Myofibroblast; Proinflammatory cytokine; Cytokine; Fibrosis; Pathogenesis; Pathology; Paracrine signalling; Macrophage; Immunology; Inflammation; Cell biology; Fascia; Medicine; Biology; Internal medicine; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173802,0.000231809,0.0001703673,0.0002228738,0.0001234253,0.0001786566,0.00006909633,0.000202874,0.0005129874],"category_scores_gemma":[0.0001238512,0.00009408917,0.0001487942,0.0001459966,0.0001463771,0.0001242088,0.0001507611,0.0002426174,0.0001648151],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008433056,"about_ca_system_score_gemma":0.00009225471,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002053673,"about_ca_topic_score_gemma":0.0003782477,"domain_scores_codex":[0.9998332,0.00003013896,0.00001697818,0.00002973317,0.00005008401,0.00003990598],"domain_scores_gemma":[0.9998987,0.00003493917,0.00002600034,0.00001102639,0.00001275331,0.00001664099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000393009,0.000008329182,0.0002824416,0.00001512729,0.00000141272,0.0000435172,0.00001721292,0.00001904755,0.9992338,0.00001113323,0.000002645342,0.000325997],"study_design_scores_gemma":[0.000009768549,0.0004451715,0.01904619,0.000006846491,0.00001642095,0.0006277807,0.0001164023,0.0005511183,0.9780441,0.00003680131,0.001092969,0.000006405112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971899,0.0006655211,0.001613751,0.00001642698,0.00000753235,0.00001524685,0.0001099636,0.000008064879,0.0003736243],"genre_scores_gemma":[0.9952057,0.0004309787,0.003209459,0.00003017617,0.000008103446,0.00006062539,0.0002539277,0.000004126165,0.0007968583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005129874,"threshold_uncertainty_score":0.001716137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02419508683954722,"score_gpt":0.3079067203817512,"score_spread":0.283711633542204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}