{"id":"W3161524032","doi":"10.1056/nejmoa2101897","title":"Left Atrial Appendage Occlusion during Cardiac Surgery to Prevent Stroke","year":2021,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":691,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto; Hamilton Health Sciences; Southlake Regional Health Center; McMaster University; Population Health Research Institute","funders":"Canadian Institutes of Health Research; Nordic Pharma Group; Institute of Circulatory and Respiratory Health; Abiomed; Boston Scientific Corporation; Hamilton Health Sciences; Abbott Diagnostics; Bristol-Myers Squibb; AstraZeneca; AtriCure; Pfizer; Heart and Stroke Foundation of Canada; Sanofi; McMaster University; Amgen","keywords":"Atrial fibrillation; Left atrial appendage occlusion; Medicine; Occlusion; Appendage; Cardiac surgery; Cardiology; Stroke (engine); Atrial Appendage; Internal medicine; Ischemic stroke; Surgery; Ischemia; Anatomy; Warfarin; Sinus rhythm","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001455162,0.0002793856,0.00119847,0.0002557822,0.0002009733,0.0004869938,0.0001892408,0.0005160947,0.001908014],"category_scores_gemma":[0.004428338,0.0001090719,0.0007064766,0.0002951301,0.0002524749,0.0002355485,0.0002629469,0.000761738,0.0001676475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000186254,"about_ca_system_score_gemma":0.0006021747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003058807,"about_ca_topic_score_gemma":0.0005521452,"domain_scores_codex":[0.9991386,0.0004604794,0.0001280688,0.00007986501,0.000119162,0.00007390364],"domain_scores_gemma":[0.9981232,0.0007400035,0.0007138269,0.00007295178,0.00009168791,0.0002583047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2508644,0.008282675,0.1303211,0.01943276,0.00630852,0.0004009083,0.0004724496,0.0006232265,0.006281703,0.001036145,0.006836324,0.5691398],"study_design_scores_gemma":[0.1651171,0.2251281,0.5588812,0.007781758,0.01154498,0.002135728,0.0003398731,0.001623132,0.003355201,0.002162124,0.02185587,0.0000750341],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8611178,0.1277525,0.0006429125,0.002100241,0.001241437,0.000695998,0.0002872413,0.00003828361,0.006123448],"genre_scores_gemma":[0.9705625,0.02592012,0.000643985,0.000679444,0.001164153,0.0004593581,0.0002175171,0.000003558721,0.0003493728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001908014,"threshold_uncertainty_score":0.007695675,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03590680924000066,"score_gpt":0.3146546179633992,"score_spread":0.2787478087233985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}