{"id":"W3161550638","doi":"10.1128/jvi.02368-20","title":"Development and Evaluation of an Ebola Virus Glycoprotein Mucin-Like Domain Replacement System as a New Dendritic Cell-Targeting Vaccine Approach against HIV-1","year":2021,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Viral Infections and Outbreaks Research","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval; University of Manitoba","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Virology; Biology; Vesicular stomatitis virus; Immunogen; Epitope; Ebola virus; Glycoprotein; Antibody; DNA vaccination; Virus; Immunization; Molecular biology; Immunology; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003290755,0.0002343301,0.0002381511,0.0001824788,0.0001259424,0.0003562382,0.0002803299,0.0003393573,0.0003228056],"category_scores_gemma":[0.0001411777,0.000108458,0.0002605059,0.00008054954,0.0001824099,0.0003003723,0.0001639499,0.0005374899,0.0001176795],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002582498,"about_ca_system_score_gemma":0.0002389874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003283641,"about_ca_topic_score_gemma":0.0002834988,"domain_scores_codex":[0.9998825,0.00002150608,0.000008245222,0.00002192683,0.00003785914,0.00002792743],"domain_scores_gemma":[0.9999624,0.000005353604,0.000006854956,0.000004736793,0.000008404108,0.00001208376],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001822265,0.0002565731,0.0002071623,0.00006275919,0.00001397943,0.00005063269,0.00002230025,0.000496916,0.9932423,0.0002204523,0.00006495739,0.005179712],"study_design_scores_gemma":[0.0002622594,0.007218968,0.001624255,0.00001630128,0.00008384034,0.0003191595,0.00003086517,0.005689376,0.9775698,0.00008650971,0.007084734,0.00001401091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990673,0.00265561,0.005200607,0.0001934323,0.00007333199,0.0001814674,0.0001231894,0.00004373478,0.0008556622],"genre_scores_gemma":[0.9881714,0.002124313,0.008228061,0.0001177538,0.00002139999,0.00009453434,0.0002748781,0.00001000133,0.0009575884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003562382,"threshold_uncertainty_score":0.001873732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02804212108724137,"score_gpt":0.3181739731772917,"score_spread":0.2901318520900503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}