{"id":"W3161795451","doi":"10.1111/mmi.14760","title":"Autorepressor PsrA is required for optimal <i>Legionella pneumophila</i> growth in <i>Acanthamoeba castellanii</i> protozoa","year":2021,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Legionella and Acanthamoeba research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Manitoba Health Research Council","keywords":"Biology; rpoS; Legionella pneumophila; Microbiology; Virulence; Legionella; Protozoa; Virulence factor; Gene; Genetics; Bacteria; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003308879,0.0003906144,0.000464471,0.0001226409,0.0001228265,0.00005361609,0.0004853376,0.0005543845,0.00002426837],"category_scores_gemma":[0.0001722562,0.0004014394,0.0003094875,0.0002946057,0.0002576821,0.000007719646,0.0004182696,0.0002659585,0.00003702057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004996531,"about_ca_system_score_gemma":0.0003746842,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005137792,"about_ca_topic_score_gemma":0.00003020162,"domain_scores_codex":[0.9969695,0.0002422114,0.0005036552,0.001230421,0.0001148841,0.0009393967],"domain_scores_gemma":[0.9986128,0.00003867902,0.0001268723,0.00070104,0.0003586347,0.0001619657],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002737525,0.0001786025,0.000906677,0.00009019278,0.00009838241,0.00030763,0.00008096732,0.00005429749,0.9860605,0.0002476868,0.01151398,0.0001873382],"study_design_scores_gemma":[0.001796084,0.0003215803,0.00005424999,0.00003154732,0.00002074242,0.0005162302,0.00005509779,0.00007212497,0.88886,0.000140364,0.107698,0.0004340312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887964,0.002346506,0.002405117,0.00287146,0.0003167674,0.001457529,0.0002555352,0.00003446133,0.001516265],"genre_scores_gemma":[0.9906998,0.000257882,0.001925684,0.003887286,0.0002466131,0.0003640016,0.0009725012,0.00009329314,0.00155295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09720053,"threshold_uncertainty_score":0.9998438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294618177080883,"score_gpt":0.2634542761023371,"score_spread":0.2505080943315283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}