{"id":"W3161898366","doi":"10.1038/s41523-021-00264-2","title":"NRG Oncology/NSABP B-47 menstrual history study: impact of adjuvant chemotherapy with and without trastuzumab","year":2021,"lang":"en","type":"article","venue":"npj Breast Cancer","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Jewish General Hospital; Montreal General Hospital","funders":"National Cancer Institute; American College of Radiology Imaging Network; Genentech; F. Hoffmann-La Roche; Breast Cancer Research Foundation","keywords":"Medicine; Trastuzumab; Amenorrhea; Gynecology; Breast cancer; Oophorectomy; Internal medicine; Oncology; Triptorelin; Obstetrics; Hysterectomy; Cancer; Hormone; Luteinizing hormone; Pregnancy; Surgery; Gonadotropin-releasing hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001351773,0.0001873674,0.0005952632,0.0001930163,0.0001669429,0.0003388374,0.0002208353,0.0002900101,0.001194219],"category_scores_gemma":[0.001858355,0.0001392243,0.0005092849,0.0002995766,0.0002111674,0.0002046356,0.0002717405,0.0005385982,0.0001537019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005879528,"about_ca_system_score_gemma":0.0008499066,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003534154,"about_ca_topic_score_gemma":0.004665944,"domain_scores_codex":[0.9994047,0.0003671805,0.00002453536,0.000045321,0.0000859102,0.00007239851],"domain_scores_gemma":[0.999111,0.0002400572,0.0002258214,0.00007890407,0.00002936974,0.0003148155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.4123539,0.007448648,0.4474189,0.0002750981,0.002901526,0.000438395,0.0001905472,0.0007358537,0.007107899,0.0002349064,0.004063086,0.1168313],"study_design_scores_gemma":[0.01958095,0.04616066,0.9255815,0.00005092642,0.001310751,0.0003390049,0.0001002485,0.0006113785,0.0009286321,0.0001062212,0.005212772,0.00001691245],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964809,0.00179937,0.00003483285,0.0003028319,0.0000284922,0.00007048123,0.0004522224,0.000003119422,0.0008278202],"genre_scores_gemma":[0.9971958,0.0008817244,0.0001168891,0.0003267796,0.00009907913,0.00005504743,0.0006387103,0.000005618378,0.00068033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003534154,"threshold_uncertainty_score":0.007148921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006946025991060778,"score_gpt":0.2821574875482367,"score_spread":0.2752114615571759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}