{"id":"W3161898366","doi":"10.1038/s41523-021-00264-2","title":"NRG Oncology/NSABP B-47 menstrual history study: impact of adjuvant chemotherapy with and without trastuzumab","year":2021,"lang":"en","type":"article","venue":"npj Breast Cancer","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre; Jewish General Hospital; Montreal General Hospital","funders":"National Cancer Institute; American College of Radiology Imaging Network; Genentech; F. Hoffmann-La Roche; Breast Cancer Research Foundation","keywords":"Medicine; Trastuzumab; Amenorrhea; Gynecology; Breast cancer; Oophorectomy; Internal medicine; Oncology; Triptorelin; Obstetrics; Hysterectomy; Cancer; Hormone; Luteinizing hormone; Pregnancy; Surgery; Gonadotropin-releasing hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008897042,0.0001939202,0.0003031644,0.00002686652,0.00003529014,0.000005811894,0.00007766269,0.0001677954,0.0001336685],"category_scores_gemma":[0.000004198464,0.000141586,0.00008649826,0.00006087555,0.0001576882,0.000004667837,0.00003940313,0.0001453065,0.000001232634],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002124114,"about_ca_system_score_gemma":0.0008623603,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002812785,"about_ca_topic_score_gemma":0.0001045892,"domain_scores_codex":[0.9990587,0.00008347756,0.0001553582,0.0003520909,0.0001322655,0.0002180654],"domain_scores_gemma":[0.9994081,0.000006212654,0.0001049808,0.0002423373,0.0001260929,0.0001123343],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002732447,0.0008791029,0.2934146,0.00003814482,0.00162782,0.00005516193,0.0008340171,0.00008024416,0.6296368,0.000005114365,0.002611917,0.0680846],"study_design_scores_gemma":[0.01202887,0.005915162,0.8788448,0.000103378,0.0003698388,0.001490995,0.0007152995,0.00007310246,0.09263751,0.000006043177,0.00717836,0.0006366592],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914497,0.007279262,0.00001813892,0.0000933958,0.0001040918,0.0002045865,0.0000441798,0.00001021699,0.0007964202],"genre_scores_gemma":[0.998639,0.000574657,0.0001196558,0.000105341,0.0001315257,0.00003086668,0.000020034,0.00003245181,0.0003464334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5854302,"threshold_uncertainty_score":0.5773708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006946025991060778,"score_gpt":0.2821574875482367,"score_spread":0.2752114615571759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}