{"id":"W3162185573","doi":"10.31234/osf.io/k56q8","title":"Polygenic risk for aggressive behaviour from late childhood through early adulthood","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; ZonMw; Rijksuniversiteit Groningen; European Science Foundation","keywords":"Polygenic risk score; Generalizability theory; Genetic association; Genome-wide association study; Psychology; Population; Predictive power; Demography; Association (psychology); Biology; Developmental psychology; Clinical psychology; Genetics; Single-nucleotide polymorphism; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006047745,0.0002440615,0.000224825,0.0006291656,0.0003260181,0.0005117569,0.0001651928,0.0002518667,0.001675418],"category_scores_gemma":[0.001820119,0.0001956754,0.0003816922,0.0007653845,0.0002679941,0.0001755747,0.0005235695,0.0005134262,0.0001742412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002283882,"about_ca_system_score_gemma":0.0004207505,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01457071,"about_ca_topic_score_gemma":0.01991094,"domain_scores_codex":[0.9996226,0.0000980676,0.00001893076,0.0001379025,0.00005922465,0.00006322228],"domain_scores_gemma":[0.9993174,0.000167084,0.0002499603,0.0001152735,0.00006352204,0.00008676292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001394594,0.00002255467,0.9849136,0.00001617482,0.0001734816,0.0001762408,0.0003197236,0.0002276368,0.003147989,0.0004015099,0.0002296551,0.01023194],"study_design_scores_gemma":[0.000001828701,0.00002373634,0.999047,0.000005940144,0.00003584498,0.0001338966,0.00005369302,0.0001723195,0.0001728204,0.0001878483,0.0001626929,0.000002473317],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967431,0.000426358,0.00126707,0.0001050816,0.000007617143,0.000004862472,0.0005564489,0.00002269386,0.0008667368],"genre_scores_gemma":[0.9977103,0.0003499733,0.000827772,0.00001410235,0.000004620969,0.000006973909,0.0004361667,0.000007474809,0.0006424483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01457071,"threshold_uncertainty_score":0.02897179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0115208921201101,"score_gpt":0.2689570362606585,"score_spread":0.2574361441405484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}