{"id":"W3162200776","doi":"10.1002/9781119745532.ch2","title":"Genetic Basis of ALS","year":2021,"lang":"nl","type":"other","venue":"","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Amyotrophic lateral sclerosis; Disease; Inheritance (genetic algorithm); Genetic heterogeneity; Identification (biology); Multifactorial Inheritance; Biology; Medicine; Genetics; Gene; Phenotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001692806,0.0002615322,0.0003492945,0.0006285294,0.000281793,0.0008261522,0.0002544718,0.0006280444,0.008715627],"category_scores_gemma":[0.0003490589,0.00006960635,0.0002192758,0.0006533608,0.0003573232,0.0003258873,0.0003771628,0.0004704855,0.002226623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004980692,"about_ca_system_score_gemma":0.0004009016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00106291,"about_ca_topic_score_gemma":0.001612978,"domain_scores_codex":[0.9998904,0.00001797477,0.0000108052,0.00002847753,0.00003595416,0.00001623396],"domain_scores_gemma":[0.9999208,0.00003106668,0.00001524072,0.000004217728,0.00001396322,0.00001460416],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000442243,0.00006974735,0.01828742,0.003072757,0.0002930922,0.01852338,0.0007129855,0.001259123,0.05394943,0.06418443,0.06961817,0.7695873],"study_design_scores_gemma":[0.00006915774,0.0001608941,0.03242488,0.002205491,0.0002765191,0.04570484,0.0004547479,0.0008649472,0.01031878,0.0504157,0.8570389,0.00006514804],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"other","genre_scores_codex":[0.09051593,0.7078754,0.008031722,0.01644001,0.001243006,0.00008169496,0.002883518,0.0006887615,0.1722399],"genre_scores_gemma":[0.3605084,0.5335048,0.008485781,0.004922621,0.001617647,0.00007103983,0.003893126,0.0002381208,0.08675843],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.008715627,"threshold_uncertainty_score":0.02915668,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.041966840238613,"score_gpt":0.3195149774919849,"score_spread":0.2775481372533719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}