{"id":"W3162255490","doi":"10.1503/jpn.200159","title":"Blood microbiota and metabolomic signature of major depression before and after antidepressant treatment: a prospective case–control study","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Microbiome; Metabolome; Metabolomics; Antidepressant; Dysbiosis; Physiology; Internal medicine; Biology; Major depressive disorder; Medicine; Bioinformatics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008620134,0.0006337657,0.0009087395,0.000956509,0.001074026,0.0008461274,0.0005987366,0.0009943235,0.00124422],"category_scores_gemma":[0.001611862,0.000773536,0.0008733515,0.001006828,0.0005197845,0.0004577877,0.000655661,0.0006240823,0.0002148933],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004799201,"about_ca_system_score_gemma":0.0002993163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004334477,"about_ca_topic_score_gemma":0.00463775,"domain_scores_codex":[0.9989305,0.0002192734,0.0001322273,0.0004659498,0.0001494882,0.0001025746],"domain_scores_gemma":[0.9991131,0.0001253615,0.0003179914,0.0001652161,0.0001150581,0.0001631736],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007928911,0.0002049494,0.9951848,0.00004327602,0.0003309761,0.0004387758,0.0001686134,0.00002816929,0.001405194,0.00003409697,0.0001224776,0.001245877],"study_design_scores_gemma":[0.00006188801,0.0004639119,0.9976212,0.00001494574,0.0002181132,0.001006257,0.000142871,0.0001599082,0.0001062467,0.00002467249,0.0001711309,0.000008799698],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985648,0.0005485934,0.0002644461,0.00002615191,0.00001108863,0.00007787895,0.0002844746,0.00000376185,0.0002188976],"genre_scores_gemma":[0.998973,0.000151653,0.0002788153,0.00004439989,0.00001762446,0.00005087774,0.0003699137,0.000002457073,0.0001111842],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004334477,"threshold_uncertainty_score":0.008618474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004266265671078507,"score_gpt":0.2484757492819265,"score_spread":0.244209483610848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}