{"id":"W3162347329","doi":"10.1016/j.celrep.2021.109152","title":"Snapshot of an influenza virus glycoprotein fusion intermediate","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Ministry of Training, Colleges and Universities","keywords":"Lipid bilayer fusion; Fusion; Glycoprotein; Hemagglutinin (influenza); Viral entry; Biology; Virus; Fusion mechanism; Biophysics; Viral membrane; Viral envelope; Cell fusion; Chemistry; Cell biology; Biochemistry; Virology; Viral replication; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007646693,0.0001708286,0.000155708,0.0002851591,0.000447735,0.0004534875,0.0003642243,0.0004533825,0.002229225],"category_scores_gemma":[0.0001730446,0.0001729346,0.0001644418,0.000185683,0.0002746814,0.0005203171,0.000306563,0.00124061,0.0004278961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004720766,"about_ca_system_score_gemma":0.0002610763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007848824,"about_ca_topic_score_gemma":0.0008046926,"domain_scores_codex":[0.9999551,0.000002764365,0.000001564521,0.000008491684,0.00001768117,0.00001452175],"domain_scores_gemma":[0.9999108,0.00001979122,0.00001251618,0.000008394109,0.00001590442,0.00003255181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004322766,0.0001250731,0.001524181,0.00009406768,0.00002266741,0.001641497,0.0002283826,0.001226588,0.9879745,0.002181764,0.0006075404,0.003941577],"study_design_scores_gemma":[0.00007763426,0.001548868,0.04234018,0.00004877633,0.00009746539,0.002944912,0.0008915641,0.02088342,0.9156334,0.003355432,0.01209783,0.00008053592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9830012,0.001069938,0.006181906,0.0003378488,0.00003800709,0.00002666749,0.0005280534,0.0002420408,0.008574227],"genre_scores_gemma":[0.9944701,0.0003838895,0.002842595,0.00007771938,0.00001384353,0.00001562126,0.000665141,0.00002313362,0.00150789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002229225,"threshold_uncertainty_score":0.007457435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05324703649479471,"score_gpt":0.3578387316423122,"score_spread":0.3045916951475175,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}