{"id":"W3162717381","doi":"10.1161/circheartfailure.120.008100","title":"Randomized Placebo-Controlled Trial of Ferric Carboxymaltose in Heart Failure With Iron Deficiency: Rationale and Design","year":2021,"lang":"en","type":"article","venue":"Circulation Heart Failure","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Canadian VIGOUR Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Heart failure; Ejection fraction; Transferrin saturation; Placebo; Iron deficiency; Internal medicine; Ferritin; Clinical endpoint; Randomized controlled trial; Multicenter trial; Anemia; Multicenter study; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01155396,0.005851389,0.009264511,0.001287084,0.001860504,0.002483882,0.001853998,0.007432357,0.02482817],"category_scores_gemma":[0.01188479,0.001627243,0.003267951,0.001335242,0.003229929,0.00209885,0.001174819,0.005161082,0.004738244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00112479,"about_ca_system_score_gemma":0.004587514,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007003002,"about_ca_topic_score_gemma":0.001428687,"domain_scores_codex":[0.9898348,0.006153483,0.0007362835,0.001472848,0.000753154,0.0010493],"domain_scores_gemma":[0.9950709,0.001575073,0.0008437685,0.0005597794,0.0009381396,0.001012339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9762502,0.005688188,0.0003281438,0.003119135,0.001252936,0.00007074545,0.00005340294,0.0002941748,0.00109123,0.0008673351,0.001905543,0.009079055],"study_design_scores_gemma":[0.9820148,0.01329068,0.0002761023,0.0001508713,0.0004892846,0.00001674129,0.00001117475,0.000292301,0.000127626,0.0005716101,0.002744491,0.00001433175],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.07463068,0.01461567,0.00761251,0.004215246,0.008928596,0.8757686,0.004443951,0.0005684277,0.009216349],"genre_scores_gemma":[0.1217536,0.003581946,0.01139422,0.004204562,0.001983336,0.8504782,0.0009862054,0.00004311974,0.005574769],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02482817,"threshold_uncertainty_score":0.08305848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01778755145908846,"score_gpt":0.2586109216212541,"score_spread":0.2408233701621657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}