{"id":"W3162717381","doi":"10.1161/circheartfailure.120.008100","title":"Randomized Placebo-Controlled Trial of Ferric Carboxymaltose in Heart Failure With Iron Deficiency: Rationale and Design","year":2021,"lang":"en","type":"article","venue":"Circulation Heart Failure","topic":"Erythropoietin and Anemia Treatment","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Heart Institute; Canadian VIGOUR Centre","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Heart failure; Ejection fraction; Transferrin saturation; Placebo; Iron deficiency; Internal medicine; Ferritin; Clinical endpoint; Randomized controlled trial; Multicenter trial; Anemia; Multicenter study; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006382185,0.0001922724,0.0009638388,0.0001491106,0.00007804013,0.00002391464,0.00002425675,0.0001402734,0.0001903776],"category_scores_gemma":[0.0003601547,0.000145444,0.0001550483,0.0003250117,0.000127181,0.00008569269,0.00001318834,0.0001636257,0.000008315287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007752935,"about_ca_system_score_gemma":0.0004632991,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004274702,"about_ca_topic_score_gemma":0.00007631827,"domain_scores_codex":[0.9981151,0.0004528014,0.0005016632,0.0003544388,0.0003749908,0.0002010372],"domain_scores_gemma":[0.9987804,0.0005707541,0.000120712,0.0002432479,0.0001807336,0.0001041534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9628339,0.0009699131,0.01253615,0.0002855339,0.0001159659,0.00005144394,0.001065806,0.003727071,0.01574464,0.000776331,0.001787718,0.0001055386],"study_design_scores_gemma":[0.9921107,0.0003048977,0.002576591,0.000177579,0.0002411414,0.0001527752,0.0004122983,0.001948044,0.001255897,0.0001138297,0.0005532277,0.0001530716],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772247,0.0007331865,0.0008433803,0.01579591,0.0000687486,0.005056484,0.000003194913,0.00003720004,0.0002372107],"genre_scores_gemma":[0.9845757,0.00002082136,0.01448125,0.000169891,0.00008001123,0.0003295077,0.00005756494,0.00001981834,0.0002653775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02927676,"threshold_uncertainty_score":0.5931032,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01778755145908846,"score_gpt":0.2586109216212541,"score_spread":0.2408233701621657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}