{"id":"W3162736988","doi":"10.1002/path.5705","title":"<scp>SMARCA4</scp> ‐deficient rhabdoid tumours show intermediate molecular features between <scp>SMARCB1</scp> ‐deficient rhabdoid tumours and small cell carcinomas of the ovary, hypercalcaemic type","year":2021,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"B.C. Women's Hospital & Health Centre; BC Children's Hospital; Children's & Women's Health Centre of British Columbia","funders":"Institut National Du Cancer; Agence Nationale de la Recherche","keywords":"SMARCA4; SMARCB1; Biology; DNA methylation; Cancer research; Epigenetics; Pathology; Medicine; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002348784,0.000298606,0.0001718425,0.001109575,0.0001989356,0.0003997291,0.0001930649,0.0003629067,0.002340749],"category_scores_gemma":[0.0004297729,0.0001709262,0.0002169775,0.0003353955,0.0005193019,0.0002226982,0.0003276577,0.0002607835,0.0004506172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002507202,"about_ca_system_score_gemma":0.0001470283,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006111177,"about_ca_topic_score_gemma":0.001051185,"domain_scores_codex":[0.9997699,0.00002473306,0.00003778116,0.0000542632,0.00005752363,0.00005578253],"domain_scores_gemma":[0.9995694,0.00008836221,0.0001796527,0.00004829532,0.00004362914,0.00007073225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005218544,0.0000297436,0.1232255,0.000161658,0.00007618429,0.01255786,0.0001981255,0.0002397697,0.8538554,0.0003383181,0.0001616644,0.008633877],"study_design_scores_gemma":[0.00004540475,0.0003769627,0.7092952,0.00002583283,0.0001290979,0.09632135,0.0005445867,0.001294116,0.1857546,0.0006338141,0.005555537,0.0000233896],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966915,0.0004628677,0.0009335626,0.00003358206,0.000003958502,0.00002122851,0.0002153909,0.0000502389,0.001587705],"genre_scores_gemma":[0.9980165,0.0001230815,0.001062201,0.00001203939,0.000003712188,0.00001283608,0.0003029418,0.000007938775,0.0004589012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002340749,"threshold_uncertainty_score":0.00783062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133376197308802,"score_gpt":0.2301637100945556,"score_spread":0.2188299481214675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}