{"id":"W3162736988","doi":"10.1002/path.5705","title":"<scp>SMARCA4</scp> ‐deficient rhabdoid tumours show intermediate molecular features between <scp>SMARCB1</scp> ‐deficient rhabdoid tumours and small cell carcinomas of the ovary, hypercalcaemic type","year":2021,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"B.C. Women's Hospital & Health Centre; BC Children's Hospital; Children's & Women's Health Centre of British Columbia","funders":"Institut National Du Cancer; Agence Nationale de la Recherche","keywords":"SMARCA4; SMARCB1; Biology; DNA methylation; Cancer research; Epigenetics; Pathology; Medicine; Genetics; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001089629,0.0003602692,0.0005833663,0.0001119744,0.000165887,0.00003472123,0.0007788947,0.000301668,0.000004246375],"category_scores_gemma":[0.0006375099,0.0002393768,0.0003420062,0.0002667675,0.0004611003,0.000007429055,0.0005728561,0.000703742,0.000003388861],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005341873,"about_ca_system_score_gemma":0.0004323096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002253078,"about_ca_topic_score_gemma":0.00002612631,"domain_scores_codex":[0.997241,0.000709517,0.0006988689,0.000401544,0.0003914761,0.0005576523],"domain_scores_gemma":[0.9976787,0.0002650878,0.0006879133,0.0007034458,0.0004876445,0.0001772024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004390013,0.0001336462,0.01653168,0.00009485347,0.00008865515,0.0001905889,0.001153852,0.001309433,0.9770387,0.00002754339,0.002763272,0.0006238188],"study_design_scores_gemma":[0.001637379,0.0009449528,0.07352076,0.0001471672,0.0005449642,0.003794936,0.002691246,0.0001111375,0.9141628,0.0004394043,0.001866393,0.0001388479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763068,0.02117296,0.0005314273,0.0003827194,0.0006932517,0.0001825073,0.00004634626,0.000008431905,0.0006755874],"genre_scores_gemma":[0.9964589,0.001726372,0.000443838,0.0004535153,0.0003104194,0.000003669494,0.0000253267,0.00005347094,0.0005244295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06287593,"threshold_uncertainty_score":0.9761504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01133376197308802,"score_gpt":0.2301637100945556,"score_spread":0.2188299481214675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}