{"id":"W3162825470","doi":"10.1016/j.vaccine.2021.05.003","title":"An open-label, single-arm study evaluating the immunogenicity and safety of the hepatitis B vaccine HepB-CpG (HEPLISAV-B®) in adults receiving hemodialysis","year":2021,"lang":"en","type":"article","venue":"Vaccine","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Norfolk General Hospital","funders":"","keywords":"Medicine; HBsAg; Hemodialysis; Immunogenicity; Hepatitis B virus; Hepatitis B; Internal medicine; Interim analysis; Hepatitis B vaccine; Population; CpG Oligodeoxynucleotide; Gastroenterology; Vaccination; Immunology; Antigen; Clinical trial; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002110806,0.0003366909,0.0009954927,0.0001117953,0.0004620178,0.00007489276,0.0005481729,0.00009385476,0.0002456593],"category_scores_gemma":[0.002645874,0.0002156268,0.00007350209,0.001340585,0.00003004275,0.0002513088,0.001101058,0.0004340032,0.000004858833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002205049,"about_ca_system_score_gemma":0.000203797,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.01618065,"about_ca_topic_score_gemma":0.09466798,"domain_scores_codex":[0.9962677,0.0009500092,0.00107216,0.0006939056,0.0005888114,0.000427422],"domain_scores_gemma":[0.9970546,0.0005812521,0.0003629671,0.001445444,0.0004536762,0.0001020782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001161346,0.003947264,0.9384091,0.0000838843,0.0003511755,0.00003794941,0.004682293,0.00002141187,0.02221359,0.0000203463,0.0001206751,0.02895093],"study_design_scores_gemma":[0.01278383,0.003939129,0.9734287,0.0006707329,0.0004483584,0.00004622233,0.001341947,0.002129523,0.004789719,0.00008712722,0.0001013577,0.0002333428],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922183,0.002617027,0.00001728725,0.002557941,0.00021255,0.001897645,0.00003078645,0.00003694335,0.0004114808],"genre_scores_gemma":[0.9970937,0.001178293,0.000682847,0.0005279072,0.000132445,0.0001386051,0.00002186959,0.0000514894,0.0001728702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07848733,"threshold_uncertainty_score":0.9903707,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930434898060572,"score_gpt":0.3379035064942775,"score_spread":0.2885991575136718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}