{"id":"W3162825470","doi":"10.1016/j.vaccine.2021.05.003","title":"An open-label, single-arm study evaluating the immunogenicity and safety of the hepatitis B vaccine HepB-CpG (HEPLISAV-B®) in adults receiving hemodialysis","year":2021,"lang":"en","type":"article","venue":"Vaccine","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Norfolk General Hospital","funders":"","keywords":"Medicine; HBsAg; Hemodialysis; Immunogenicity; Hepatitis B virus; Hepatitis B; Internal medicine; Interim analysis; Hepatitis B vaccine; Population; CpG Oligodeoxynucleotide; Gastroenterology; Vaccination; Immunology; Antigen; Clinical trial; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003882899,0.001225907,0.00196705,0.0003290215,0.0005981965,0.0007104658,0.0005752411,0.001519882,0.002938005],"category_scores_gemma":[0.002600908,0.0006016034,0.001114706,0.0002929413,0.001011321,0.001208543,0.0004343484,0.001851924,0.0004357554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004566309,"about_ca_system_score_gemma":0.00124352,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004359338,"about_ca_topic_score_gemma":0.0005331033,"domain_scores_codex":[0.9987859,0.0007075258,0.0001065278,0.0001546021,0.0001265732,0.0001187931],"domain_scores_gemma":[0.9977238,0.0006112016,0.0006003734,0.0002204589,0.0002409597,0.0006031694],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8637765,0.09365024,0.01070149,0.0004392022,0.0007874706,0.00008923726,0.0002980442,0.0003575887,0.0118778,0.00006281344,0.0004451922,0.01751439],"study_design_scores_gemma":[0.3044518,0.6805297,0.01254345,0.00001877552,0.0002586335,0.00005712926,0.00007108746,0.0003846292,0.001182704,0.0000612648,0.0004243374,0.00001656572],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972768,0.0002733655,0.0002829636,0.00006423397,0.00004809948,0.001652754,0.0001870632,0.00001417087,0.0002004225],"genre_scores_gemma":[0.993198,0.0003327988,0.001196543,0.0003329518,0.0002217909,0.003603818,0.0004570218,0.000006255325,0.0006508887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003882899,"threshold_uncertainty_score":0.02053499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04930434898060572,"score_gpt":0.3379035064942775,"score_spread":0.2885991575136718,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}