{"id":"W3163015339","doi":"10.1016/j.ejmg.2021.104245","title":"Defining the natural history of rare genetic liver diseases: Lessons learned from the NAPPED initiative","year":2021,"lang":"en","type":"article","venue":"European Journal of Medical Genetics","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; University Health Network","funders":"National Institutes of Health; Rijksuniversiteit Groningen","keywords":"Workload; Natural history; Summit; Medicine; CRFS; Psychology; Computer science; Geography; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01892868,0.0005176135,0.0011143,0.00194336,0.0006919467,0.003302559,0.001833444,0.002251399,0.003759925],"category_scores_gemma":[0.03174123,0.0003165253,0.0006831735,0.001360625,0.003823407,0.005242461,0.00558213,0.004636244,0.0005060239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003466397,"about_ca_system_score_gemma":0.005241382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00603581,"about_ca_topic_score_gemma":0.00936035,"domain_scores_codex":[0.9956374,0.001868401,0.0003406977,0.0009549452,0.0008626874,0.000335971],"domain_scores_gemma":[0.9586977,0.0277779,0.00238001,0.002308991,0.004847985,0.003987381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.00215302,0.0003248434,0.09674256,0.001687256,0.0006545882,0.001773078,0.002450649,0.002598662,0.0027688,0.09026951,0.07080998,0.7277672],"study_design_scores_gemma":[0.0004909401,0.0009987534,0.1020785,0.005943479,0.0006194866,0.005833747,0.003877519,0.00314763,0.003659469,0.219268,0.6537922,0.0002902852],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.2077864,0.2013753,0.04830372,0.4807021,0.006256411,0.000189549,0.005909477,0.0005037299,0.04897343],"genre_scores_gemma":[0.6679072,0.1478595,0.06632647,0.09665247,0.00953576,0.0003951288,0.005094583,0.0006699752,0.005558972],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01892868,"threshold_uncertainty_score":0.1001056,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04253189906647684,"score_gpt":0.2687547621078299,"score_spread":0.2262228630413531,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}