{"id":"W3163027070","doi":"","title":"Therasphere yttrium-90 glass microspheres combined with chemotherapy versus chemotherapy alone in second-line treatment of patients with metastatic colorectal carcinoma of the liver: Protocol for the EPOCH phase 3 randomized clinical trial","year":2019,"lang":"en","type":"article","venue":"UCL Discovery (University College London)","topic":"Hepatocellular Carcinoma Treatment and Prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Oxaliplatin; Irinotecan; Regimen; Internal medicine; Colorectal cancer; Clinical endpoint; Oncology; Chemotherapy; Chemotherapy regimen; Progression-free survival; Randomized controlled trial; Surgery; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01106659,0.004839878,0.005669424,0.0009751292,0.001183776,0.002101311,0.002653537,0.003575665,0.0188066],"category_scores_gemma":[0.007118652,0.001489991,0.003232438,0.001711931,0.001737773,0.001631705,0.00122503,0.004670823,0.002789684],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002390317,"about_ca_system_score_gemma":0.007553451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001627049,"about_ca_topic_score_gemma":0.004176447,"domain_scores_codex":[0.9953197,0.003090162,0.0002764869,0.0003785761,0.0003749582,0.0005602299],"domain_scores_gemma":[0.9963762,0.0007094921,0.001090631,0.0003802624,0.0005287224,0.0009147486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9884678,0.004478158,0.0002189527,0.0007155571,0.000464996,0.00002741247,0.00003378702,0.0004327418,0.0008506111,0.0001566805,0.001427972,0.002725391],"study_design_scores_gemma":[0.9646704,0.03085394,0.0005492084,0.00008020754,0.0003319723,0.00001845011,0.00001847455,0.0005353414,0.0002603055,0.00024032,0.002423815,0.00001738019],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.1924436,0.003625499,0.004642898,0.001705692,0.002176958,0.7743993,0.01208684,0.0005517317,0.008367536],"genre_scores_gemma":[0.1505103,0.002615459,0.009368483,0.002434826,0.0006353277,0.8237216,0.003786224,0.00007550378,0.006852285],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.0188066,"threshold_uncertainty_score":0.06291437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04043829768305494,"score_gpt":0.2826633567970767,"score_spread":0.2422250591140218,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}