{"id":"W3163104866","doi":"10.1503/cmaj.78702","title":"To act or not to act","year":2021,"lang":"en","type":"letter","venue":"Canadian Medical Association Journal","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; University of Toronto","funders":"","keywords":"Sorafenib; Psoriasis; Angiogenesis; Medicine; Vascular endothelial growth factor; Cancer research; Hepatocellular carcinoma; Platelet-derived growth factor receptor; Growth factor; Immunology; Receptor; Internal medicine; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000645705,0.0004061096,0.0003236209,0.0002429476,0.001305174,0.0009599472,0.0005190272,0.005063531,0.03029983],"category_scores_gemma":[0.004997412,0.0001054212,0.0003473485,0.0001683905,0.001135394,0.0009409233,0.0006205128,0.004734627,0.01792337],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001233093,"about_ca_system_score_gemma":0.001200557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002124619,"about_ca_topic_score_gemma":0.002577377,"domain_scores_codex":[0.9991658,0.0002271269,0.00004382525,0.0001051187,0.0002003123,0.0002577714],"domain_scores_gemma":[0.9990529,0.0002533621,0.00009154333,0.00007617575,0.0002037776,0.0003221324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003557877,0.0002056952,0.005689524,0.0002627777,0.00003889673,0.03507658,0.0007080756,0.0002361629,0.002608054,0.02070727,0.8398914,0.09421977],"study_design_scores_gemma":[0.00006436153,0.00008667252,0.002249654,0.0002093939,0.00001625042,0.04476142,0.0004593209,0.0004369936,0.0009100496,0.009185068,0.9415854,0.00003540278],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"editorial","genre_scores_codex":[0.01827718,0.00803783,0.001584463,0.6458024,0.04210537,0.0001689474,0.0003124524,0.0002474089,0.283464],"genre_scores_gemma":[0.1955063,0.005431332,0.001219181,0.4835535,0.03116956,0.0001544553,0.0002332902,0.0001074147,0.282625],"genre_candidate":"editorial","genre_consensus":null,"teacher_disagreement_score":0.03029983,"threshold_uncertainty_score":0.1013631,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196275540531416,"score_gpt":0.2437133059006462,"score_spread":0.231750550495332,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}